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Testing Data (Staining of mouse human peripheal blood monocytes with Mouse anti Human CD200R: Alexa Fluor 647 (MBS212647A647))

Mouse CD200R Monoclonal Antibody | anti-CD200R antibody

MOUSE ANTI HUMAN CD200R:RPE

Gene Names
CD200R1; OX2R; MOX2R; CD200R; HCRTR2
Applications
Flow Cytometry, Functional Assay
Synonyms
CD200R; Monoclonal Antibody; MOUSE ANTI HUMAN CD200R:RPE; anti-CD200R antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
OX108
Form/Format
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilised
Sequence Length
348
Applicable Applications for anti-CD200R antibody
Flow cytometry (FC/FACS)
Application Notes
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul
Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/10
Reconstitution
Reconstitute with 1.0 ml distilled water
Perservative Stabilisers
Immunogen
Fusion protein hCD200RCD4d3+4
Buffer Solution
Target Species
Human
Preparation and Storage
Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of reconstitution.

Testing Data

(Staining of mouse human peripheal blood monocytes with Mouse anti Human CD200R: Alexa Fluor 647 (MBS212647A647))

Testing Data (Staining of mouse human peripheal blood monocytes with Mouse anti Human CD200R: Alexa Fluor 647 (MBS212647A647))

Testing Data

(Staining of human peripheral blood lymphocytes probed with Mouse anti Human CD200R)

Testing Data (Staining of human peripheral blood lymphocytes probed with Mouse anti Human CD200R)
Related Product Information for anti-CD200R antibody
Mouse anti Human CD200R antibody, clone OX108 recognizes human CD200R, a cell surface glycoprotein (also known as OX2R). In humans CD200R is expressed primarily by peripheral blood monocytes and neutrophils but also by other leucocytes including T-lymphocytes and mast cells (Wrightet al. 2003). Studies suggest that CD200-CD200R interaction may be involved in the control of myeloid cellular function. Levels of expression on resting perispheral blood cells are relatively low.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39,056 Da
NCBI Official Full Name
cell surface glycoprotein CD200 receptor 1 isoform a
NCBI Official Synonym Full Names
CD200 receptor 1
NCBI Official Symbol
CD200R1
NCBI Official Synonym Symbols
OX2R; MOX2R; CD200R; HCRTR2
NCBI Protein Information
cell surface glycoprotein CD200 receptor 1; CD200 cell surface glycoprotein receptor; MOX2 receptor; cell surface glycoprotein OX2 receptor 1; cell surface glycoprotein receptor CD200
UniProt Protein Name
Cell surface glycoprotein CD200 receptor 1
UniProt Gene Name
CD200R1
UniProt Synonym Gene Names
CD200R; CRTR2; MOX2R; OX2R
UniProt Entry Name
MO2R1_HUMAN

NCBI Description

This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Uniprot Description

CD200R: Receptor for the CD200/OX2 cell surface glycoprotein. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200. Belongs to the CD200R family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 3q13.2

Cellular Component: integral to membrane; plasma membrane; extracellular region; receptor complex

Molecular Function: protein binding

Biological Process: regulation of immune response; viral reproduction

Research Articles on CD200R

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Product Notes

The CD200R cd200r1 (Catalog #AAA213769) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD200R can be used in a range of immunoassay formats including, but not limited to, Flow cytometry (FC/FACS). Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/10. Researchers should empirically determine the suitability of the CD200R cd200r1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD200R, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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