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Western Blot (WB) (Western blot analysis of extracts from COLO205 and Jurkat cells, using SLCO1B1 antibody.)

anti-Human SLCO1B1 Antibody | anti-SLCO1B1 antibody

SLCO1B1 Antibody

Gene Names
SLCO1B1; LST1; HBLRR; LST-1; OATP2; OATPC; OATP-C; OATP1B1; SLC21A6
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
SLCO1B1; SLCO1B1 Antibody; Solute carrier family 21 member 6; Sodium-independent organic anion-transporting polypeptide 2; OATP 2; Liver-specific organic anion transporter 1; LST-1; OATP-C; anti-SLCO1B1 antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
SLCO1B1 antibody detects endogenous levels of total SLCO1B1 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
691
Applicable Applications for anti-SLCO1B1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:40000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human SLCO1B1.
Preparation and Storage
Store at-20 degree C for 1 year.

Western Blot (WB)

(Western blot analysis of extracts from COLO205 and Jurkat cells, using SLCO1B1 antibody.)

Western Blot (WB) (Western blot analysis of extracts from COLO205 and Jurkat cells, using SLCO1B1 antibody.)
References
Kirchgessner T.G., J. Biol. Chem. 274:37161-37168(1999). Keppler D., J. Biol. Chem. 275:23161-23168(2000). Venter J.C., Submitted (JUL-2005).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
76,449 Da
NCBI Official Full Name
solute carrier organic anion transporter family member 1B1
NCBI Official Synonym Full Names
solute carrier organic anion transporter family member 1B1
NCBI Official Symbol
SLCO1B1
NCBI Official Synonym Symbols
LST1; HBLRR; LST-1; OATP2; OATPC; OATP-C; OATP1B1; SLC21A6
NCBI Protein Information
solute carrier organic anion transporter family member 1B1
UniProt Protein Name
Solute carrier organic anion transporter family member 1B1
UniProt Gene Name
SLCO1B1
UniProt Synonym Gene Names
LST1; OATP1B1; OATP2; OATPC; SLC21A6; LST-1; OATP-2

NCBI Description

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009]

Uniprot Description

Mediates the Na+-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. Involved in the clearance of bile acids and organic anions from the liver.

Research Articles on SLCO1B1

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Product Notes

The SLCO1B1 slco1b1 (Catalog #AAA858137) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The SLCO1B1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLCO1B1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:40000. Researchers should empirically determine the suitability of the SLCO1B1 slco1b1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLCO1B1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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