Testing Data
Rat anti-Mouse CD200 Monoclonal Antibody | anti-CD200 antibody
Anti-Mouse CD200, Biotin (Clone OX90) (rat IgG2a)
Gene Names
CD200; MRC; MOX1; MOX2; OX-2
Reactivity
Mouse
Synonyms
CD200; Monoclonal Antibody; Anti-Mouse CD200; Biotin (Clone OX90) (rat IgG2a); Anti-Mouse CD200 (OX2) Monoclonal Antibody; anti-CD200 antibody
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
Rat IGg2a
Clone Number
OX90
Specificity
CD200 (Mouse CD200 (OX2))
Form/Format
Biotin
Concentration
Antibody Concentration: 0.1 mg/ml (varies by lot)
Sequence Length
269
Immunogen
mouse CD200-rat CD4 fusion protein
Donor
Rat spleen
Fusion Partner
Y3 myeloma
Presentation
Biotin/FITC/PE conjugated IgG buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.
Preparation and Storage
For all formats, store at 4 degree C. DO NOT FREEZE PE conjugates. For long term storage (Purified, Biotin and FITC), aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
Testing Data
Testing Data
Related Product Information for anti-CD200 antibody
anti-mouse CD200 monoclonal antibody reacts with CD200 (OX2), a highly conserved type I membrane glycoprotein that is expressed on a variety of cell types including thymocytes, some T cells, endothelial and follicular dendritc cells, and brain tissue (neurons). CD200 consists of 2 immunoglobulin (Ig) domains, a Cterminus transmembrane domain and a small cytoplasmic domain (19 aa) which lacks signaling motifs. CD200 is the ligand for CD200 receptor (CD200R), which is very similar in structure to CD200 except that it has a larger cytoplasmic domain (67 aa), and its expression is restricted to myeloid-derived antigen presenting cells (APC's) and certain populations of T cells. Blocking of CD200/CD200R interactions decreases myeloid cell inhibitory thresholds which results in enhanced immune activation. This clone is suitable for use in flow cytometry, immunohistochemistry (frozen sections) and ELISA
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
31,264 Da
NCBI Official Full Name
CD200 antigen, isoform CRA_a
NCBI Official Synonym Full Names
CD200 molecule
NCBI Official Symbol
CD200
NCBI Official Synonym Symbols
MRC; MOX1; MOX2; OX-2
NCBI Protein Information
OX-2 membrane glycoprotein; CD200 antigen; MRC OX-2 antigen; antigen identified by monoclonal antibody MRC OX-2
UniProt Protein Name
OX-2 membrane glycoprotein
Protein Family
UniProt Gene Name
CD200
UniProt Synonym Gene Names
MOX1; MOX2
UniProt Entry Name
OX2G_HUMAN
NCBI Description
The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.
Subunit structure: Interacts with CD200R1.
Subcellular location: Cell membrane; Single-pass type I membrane protein.
Sequence similarities: Contains 1 Ig-like C2-type (immunoglobulin-like) domain.Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Research Articles on CD200
Similar Products
Product Notes
The CD200 cd200 (Catalog #AAA520609) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse CD200, Biotin (Clone OX90) (rat IgG2a) reacts with Mouse and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "CD200, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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