Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD1a antibody. Counter stained with hematoxylin.)
Rabbit anti-Human CD1a Monoclonal Antibody | anti-CD1a antibody
CD1a Antibody
Gene Names
CD1A; R4; T6; CD1; FCB6; HTA1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
ProA affinity purified
Synonyms
CD1a; Monoclonal Antibody; CD1a Antibody; CD 1a antibody; CD1 antibody; CD1a antibody; CD1A Antigen antibody; CD1A antigen; a polypeptide antibody; CD1a molecule antibody; CD1A_HUMAN antibody; cluster of differentiation 1 A antibody; cortical thymocyte antigen CD1A antibody; differentiation antigen CD1 alpha 3 antibody; epidermal dendritic cell marker CD1a antibody; FCB 6 antibody; FCB6 antibody; HTA 1 antibody; HTA1 antibody; hTa1 thymocyte antigen antibody; OTTHUMP00000018907 antibody; R 4 antibody; R4 antibody; T 6 antibody; T-cell surface antigen T6/Leu-6 antibody; T-cell surface glycoprotein CD1a antibody; T6 antibody; anti-CD1a antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Clone Number
JM21-33
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-CD1a antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500
IHC: 1:50-1:200
IHC: 1:50-1:200
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD1a antibody. Counter stained with hematoxylin.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD1a antibody. Counter stained with hematoxylin.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-CD1a antibody. Counter stained with hematoxylin.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-CD1a antibody. Counter stained with hematoxylin.)
Related Product Information for anti-CD1a antibody
The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. CD1 antigens are associated with beta-2-Microglobulin and expressed on cortical thymocytes, Langerhans cells, a B cell subset and some dendritic cells. Specifically, CD1A is a marker for Langerhans cell histiocytosis (LCH) and is found on interdigitating cells. Adaptor-protein complexes and CD1-associated chaperones control CD1 trafficking, and the development and activation of CD1-restricted T cells. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. The human CD1 genes are all closely linked in a cluster mapping at chromosome 1q23.1.
Product Categories/Family for anti-CD1a antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
37,077 Da
NCBI Official Full Name
T-cell surface glycoprotein CD1a
NCBI Official Synonym Full Names
CD1a molecule
NCBI Official Symbol
CD1A
NCBI Official Synonym Symbols
R4; T6; CD1; FCB6; HTA1
NCBI Protein Information
T-cell surface glycoprotein CD1a
UniProt Protein Name
T-cell surface glycoprotein CD1a
Protein Family
UniProt Gene Name
CD1A
UniProt Synonym Gene Names
hTa1 thymocyte antigen
NCBI Description
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Uniprot Description
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
Research Articles on CD1a
Similar Products
Product Notes
The CD1a cd1a (Catalog #AAA9436353) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD1a Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD1a can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the CD1a cd1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD1a, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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