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Flow Cytometry (FC/FACS) (C57BL/6 murine splenocytes are stained with Anti-Mouse CD11a Monoclonal Antibody(PerCP/Cy5.5 Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.)

Rat anti-Mouse CD11a Monoclonal Antibody | anti-CD11a antibody

Anti-Mouse CD11a Monoclonal Antibody (PerCP/Cy5.5 Conjugated)

Gene Names
Itgal; Cd11a; LFA-1; Ly-15; Ly-21; (p180); LFA-1A
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay
Synonyms
CD11a; Monoclonal Antibody; Anti-Mouse CD11a Monoclonal Antibody (PerCP/Cy5.5 Conjugated); Integrin alpha-L; Itgal; CD11 antigen-like family member A; LFA-1A; Lymphocyte antigen 15; Ly-15; anti-CD11a antibody
Ordering
For Research Use Only!
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
FD441.8
Form/Format
Liquid; PBS with 0.05% Proclin300, 1% BSA
Sequence Length
1163
Applicable Applications for anti-CD11a antibody
Flow Cytometry (FC/FACS)
Conjugation
PerCP/Cy5.5
Preparation and Storage
Store at 2-8 degree C and protected from prolonged exposure to light. Do not freeze.

Flow Cytometry (FC/FACS)

(C57BL/6 murine splenocytes are stained with Anti-Mouse CD11a Monoclonal Antibody(PerCP/Cy5.5 Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.)

Flow Cytometry (FC/FACS) (C57BL/6 murine splenocytes are stained with Anti-Mouse CD11a Monoclonal Antibody(PerCP/Cy5.5 Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.)
Related Product Information for anti-CD11a antibody
CD11a is a 180 kD glycoprotein, also known as alphaL integrin, LFA-1 alpha, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).
References
1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Springer TA. 1994. Cell 76:301. 3. Lub M, et al. 1995. Immunol. Today 16:479.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Integrin alpha-L
NCBI Official Synonym Full Names
integrin alpha L
NCBI Official Symbol
Itgal
NCBI Official Synonym Symbols
Cd11a; LFA-1; Ly-15; Ly-21; (p180); LFA-1A
NCBI Protein Information
integrin alpha-L
UniProt Protein Name
Integrin alpha-L
UniProt Gene Name
Itgal
UniProt Synonym Gene Names
Lfa-1; Ly-15; LFA-1A; Ly-15
UniProt Entry Name
ITAL_MOUSE

Uniprot Description

ITGAL: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Belongs to the integrin alpha chain family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Cell surface; Cell adhesion

Cellular Component: cell surface; membrane; integral to membrane; immunological synapse; intercellular junction; integrin complex; external side of plasma membrane

Molecular Function: protein heterodimerization activity; metal ion binding; protein complex binding; ICAM-3 receptor activity; cell adhesion molecule binding

Biological Process: integrin-mediated signaling pathway; cell-matrix adhesion; activated T cell proliferation; positive regulation of calcium-mediated signaling; signal transduction; receptor clustering; heterophilic cell adhesion; leukocyte adhesion; cell-cell adhesion; cell surface receptor linked signal transduction; regulation of cell-cell adhesion; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; positive regulation of cell-cell adhesion; positive regulation of T cell proliferation; cell adhesion

Research Articles on CD11a

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Product Notes

The CD11a itgal (Catalog #AAA2556849) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse CD11a Monoclonal Antibody (PerCP/Cy5.5 Conjugated) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD11a can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the CD11a itgal for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD11a, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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