Mouse anti-Human CBY1 Monoclonal Antibody | anti-CBY1 antibody

CBY1 (HRIHFB2025, ARB1, C22orf2, CBY, PGEA1, Protein Chibby Homolog 1, ARPP-binding Protein, Cytosolic Leucine-rich Protein, PIGEA-14, PKD2 Interactor, Golgi and Endoplasmic Reticulum-associated 1) (PE)

Cat. Num. AAA6156904

• Gene Names: CBY1; CBY; arb1; PGEA1; C22orf2; Chibby1; PIGEA14; PIGEA-14; HS508I15A
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CBY1; Monoclonal Antibody; CBY1 (HRIHFB2025; ARB1; C22orf2; CBY; PGEA1; Protein Chibby Homolog 1; ARPP-binding Protein; Cytosolic Leucine-rich Protein; PIGEA-14; PKD2 Interactor; Golgi and Endoplasmic Reticulum-associated 1) (PE); anti-CBY1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1,k
• Clone Number: 2F2
• Specificity: Recognizes human CBY1.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
• Sequence Length: 126

• Applicable Applications for anti-CBY1 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Partial recombinant corresponding to aa18-127 from CBY1 (NP_056188) with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: SASLSNLHSLDRSTREVELGLEYGSPTMNLAGQSLKFENGQWIAETGVSGGVDRREVQRLRRRNQQLEEENNLLRLKVDILLDMLSESTAESHLMEKELDELRISRKRK*
• Conjugate: PE
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (38.1kD).)

Testing Data

(Detection limit for recombinant GST tagged CBY1 is ~0.1ng/ml as a capture antibody.)

Related Product Information for anti-CBY1 antibody

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. CBY1 has been shown to interact with Beta-catenin.

Product Categories/Family for anti-CBY1 antibody

Antibodies; Golgi Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 7656942
• NCBI GeneID: 25776
• NCBI Accession #: NP_056188
• NCBI GenBank Nucleotide #: NM_015373
• UniProt Accession #: Q9Y3M2
• NCBI Official Full Name: protein chibby homolog 1 isoform a
• NCBI Official Synonym Full Names: chibby family member 1, beta catenin antagonist
• NCBI Official Symbol: CBY1
• NCBI Official Synonym Symbols: CBY; arb1; PGEA1; C22orf2; Chibby1; PIGEA14; PIGEA-14; HS508I15A
• NCBI Protein Information: protein chibby homolog 1
• UniProt Protein Name: Protein chibby homolog 1
• Protein Family: Protein chibby
• UniProt Gene Name: CBY1
• UniProt Synonym Gene Names: ARB1; C22orf2; CBY; PGEA1; HRIHFB2025
• UniProt Entry Name: CBY1_HUMAN

NCBI Description

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]