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Immunohistochemistry (IHC) (Anti-CBR3 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Mouse anti-Human CBR3 Monoclonal Antibody | anti-CBR3 antibody

Mouse Monoclonal [clone AT3C5] (IgG1,k) to Human CBR3

Gene Names
CBR3; hCBR3; SDR21C2; HEL-S-25
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Protein G Purified
Synonyms
CBR3; Monoclonal Antibody; Mouse Monoclonal [clone AT3C5] (IgG1; k) to Human CBR3; Anti-CBR3 Antibody (clone AT3C5) IHC-plus; Carbonyl reductase [NADPH] 3; Carbonyl reductase (NADPH) 3; Carbonyl reductase 3; HCBR3; SDR21C2; Human CBR3; anti-CBR3 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
AT3C5
Specificity
CBR3 (1-277aa)
Purity/Purification
Protein G Purified
Form/Format
PBS, pH 7.4, 0.1% sodium azide
Sequence Length
277
Applicable Applications for anti-CBR3 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA, IHC-P (5 ug/ml), WB (1:1000 - 1:2000)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Target Species
Human
Immunogen Description
Recombinant CBR3 (1-277aa) purified from E Coli
Immunogen Type
Recombinant protein
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

(Anti-CBR3 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-CBR3 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC)

(Anti-CBR3 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-CBR3 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC)

(Anti-CBR3 antibody IHC of human brain, cortex, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-CBR3 antibody IHC of human brain, cortex, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Western Blot (WB)

(Western analysis of HepG2 cell lysate.)

Western Blot (WB) (Western analysis of HepG2 cell lysate.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
874
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
30,850 Da
NCBI Official Full Name
carbonyl reductase
NCBI Official Synonym Full Names
carbonyl reductase 3
NCBI Official Symbol
CBR3
NCBI Official Synonym Symbols
hCBR3; SDR21C2; HEL-S-25
NCBI Protein Information
carbonyl reductase [NADPH] 3; carbonyl reductase [NADPH] 3; carbonyl reductase (NADPH) 3; epididymis secretory protein Li 25; NADPH-dependent carbonyl reductase 3; short chain dehydrogenase/reductase family 21C, member 2
UniProt Protein Name
Carbonyl reductase [NADPH] 3
Protein Family
UniProt Gene Name
CBR3
UniProt Entry Name
CBR3_HUMAN

NCBI Description

Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008]

Uniprot Description

CBR3: Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro). Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Protein type: EC 1.1.1.184; Oxidoreductase; Lipid Metabolism - arachidonic acid

Chromosomal Location of Human Ortholog: 21q22.2

Cellular Component: nucleoplasm; extracellular space; cytoplasm; cytosol

Molecular Function: 3-keto sterol reductase activity; carbonyl reductase (NADPH) activity

Biological Process: phylloquinone catabolic process; cognition

Research Articles on CBR3

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Product Notes

The CBR3 cbr3 (Catalog #AAA245463) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone AT3C5] (IgG1,k) to Human CBR3 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CBR3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA, IHC-P (5 ug/ml), WB (1:1000 - 1:2000) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the CBR3 cbr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CBR3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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