Mouse Casein kinase I isoform alpha Monoclonal Antibody | anti-CSNK1A1 antibody
Mouse Anti Human Casein kinase I isoform alpha
Gene Names
CSNK1A1; CK1; CK1a; CKIa; HLCDGP1; PRO2975; HEL-S-77p
Applications
ELISA, Western Blot
Purity
CSNK1A1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Synonyms
Casein kinase I isoform alpha; Monoclonal Antibody; Mouse Anti Human Casein kinase I isoform alpha; CSNK1A1 Antibody; Mouse Anti Human; CKI-alpha; CK1; CSNK1A1; HLCDGP1; PRO2975; anti-CSNK1A1 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2b heavy chain and kappa light chain
Clone Number
PAT2E2AT
Purity/Purification
CSNK1A1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Form/Format
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Sequence Length
365
Applicable Applications for anti-CSNK1A1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
CSNK1A1 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1000 ~ 2000. Recommended starting dilution is 1:1000.
Immunogen
Anti-human CSNK1A1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CSNK1A1 amino acids 1-337 purified from E Coli.
Preparation and Storage
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
12 months at -20 degree C. 1 month at 4 degree C.
12 months at -20 degree C. 1 month at 4 degree C.
Related Product Information for anti-CSNK1A1 antibody
Introduction: Caseine Kinase 1 alpha belongs is a member of the protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily. The CK1 isoforms - alpha, beta, gamma, delta, epsilon and their splice variants are involved in diverse cellular processes including membrane trafficking, circadian rhythm, cell cycle progression, chromosome segregation, apoptosis and cellular differentiation. Possibly CSNK1A1 can phosphorylate a large number of proteins and is involved in Wnt signaling where it phosphorylates CTNNB1 on Ser45. CSNK1A1 also interacts with the Axin complex.
Product Categories/Family for anti-CSNK1A1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
37,567 Da
NCBI Official Full Name
casein kinase I isoform alpha isoform 1
NCBI Official Synonym Full Names
casein kinase 1, alpha 1
NCBI Official Symbol
CSNK1A1
NCBI Official Synonym Symbols
CK1; CK1a; CKIa; HLCDGP1; PRO2975; HEL-S-77p
NCBI Protein Information
casein kinase I isoform alpha; CKI-alpha; clock regulator kinase; down-regulated in lung cancer; epididymis secretory sperm binding protein Li 77p
UniProt Protein Name
Casein kinase I isoform alpha
Protein Family
UniProt Gene Name
CSNK1A1
UniProt Synonym Gene Names
CKI-alpha
UniProt Entry Name
KC1A_HUMAN
Uniprot Description
CK1A: an ubiquitous protein kinase of the CK1 family. Participates in Wnt signaling. Phosphorylates beta catenin, marking it for beta-TRCp-mediated ubiquitinylation and proteasomal degradation.
Protein type: Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, CK1; EC 2.7.11.1; CK1 group; CK1 family
Chromosomal Location of Human Ortholog: 5q32
Cellular Component: centrosome; membrane; cytoplasm; nuclear speck; mRNA cleavage and polyadenylation specificity factor complex; cytosol
Molecular Function: protein serine/threonine kinase activity; protein binding; ATP binding; protein kinase activity
Biological Process: regulation of cell shape; mitosis; peptidyl-serine phosphorylation; cell surface receptor linked signal transduction; Wnt receptor signaling pathway; cell division; signal transduction; protein amino acid phosphorylation; phagocytosis
Research Articles on CSNK1A1
1. Casein kinase 1 alpha specifically phosphorylates Jade-1 at an unprimed SLS phosphorylation site.
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Product Notes
The CSNK1A1 csnk1a1 (Catalog #AAA140221) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Casein kinase I isoform alpha can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). CSNK1A1 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1000 ~ 2000. Recommended starting dilution is 1:1000. Researchers should empirically determine the suitability of the CSNK1A1 csnk1a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Casein kinase I isoform alpha, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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