Western Blot (WB)
(Western blot detection of C17orf53 in Jurkat, A549, MCF7 and Hela cell lysates using C17orf53 mouse mAb (1:1000 diluted).Predicted band size:70KDa.Observed band size:70KDa.)
Mouse anti-Human C17orf53 Monoclonal Antibody | anti-C17orf53 antibody
Anti-C17orf53 Mouse mAb
Reactivity
Human
Applications
Western Blot
Purity
Affinity purified
Synonyms
C17orf53; Monoclonal Antibody; Anti-C17orf53 Mouse mAb; Chromosome 17 open reading frame 53; CQ053_HUMAN; FLJ11594; Hypothetical protein LOC78995; MGC3130; Uncharacterized protein C17orf53; anti-C17orf53 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
7E1-B11-F3
Purity/Purification
Affinity purified
Form/Format
Purified antibody in PBS with 0.05% sodium azide.
Sequence Length
646
Applicable Applications for anti-C17orf53 antibody
Western Blot (WB)
Application Notes
Western Blot (WB): 1/500-1/2000
ELISA (EIA): 1/1000
ELISA (EIA): 1/1000
Immunogen
Purified recombinant fragment of human C17ORF53 (AA: 282-527) expressed in E Coli.
Conjugation
Unconjugated
Modification
Unmodification
Preparation and Storage
Store at 4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycles.
Western Blot (WB)
(Western blot detection of C17orf53 in Jurkat, A549, MCF7 and Hela cell lysates using C17orf53 mouse mAb (1:1000 diluted).Predicted band size:70KDa.Observed band size:70KDa.)
Western Blot (WB)
(Western blot detection of C17orf53 in Jurkat, A549, MCF7 and Hela cell lysates using C17orf53 mouse mAb (1:1000 diluted).Predicted band size:70KDa.Observed band size:70KDa.)
Related Product Information for anti-C17orf53 antibody
Entrez Summary: C17orf53 (chromosome 17 open reading frame 53) is a 647 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1, 200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
69.8 kDa
NCBI Official Full Name
uncharacterized protein C17orf53 isoform 2
NCBI Official Synonym Full Names
chromosome 17 open reading frame 53
NCBI Official Symbol
C17orf53
NCBI Protein Information
uncharacterized protein C17orf53
UniProt Protein Name
Uncharacterized protein C17orf53
UniProt Gene Name
C17orf53
Uniprot Description
C17orf53: 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 17q21.31
Research Articles on C17orf53
1. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
Similar Products
Product Notes
The C17orf53 c17orf53 (Catalog #AAA476655) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-C17orf53 Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's C17orf53 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot (WB): 1/500-1/2000 ELISA (EIA): 1/1000. Researchers should empirically determine the suitability of the C17orf53 c17orf53 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C17orf53, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
