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Quality Control (Western blot analysis of immunized recombinant protein, using anti-BTG1 monoclonal antibody. )

Mouse anti-Human BTG1 Monoclonal Antibody | anti-BTG1 antibody

Mouse monoclonal antibody Anti-Human BTG1

Reactivity
Human
Applications
Dot Blot
Synonyms
BTG1; Monoclonal Antibody; Mouse monoclonal antibody Anti-Human BTG1; Homo sapiens B-cell translocation gene 1; anti-proliferative (BTG1); mRNA; anti-BTG1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2095C1a
Concentration
100 ug/ml (1.0 ml) (varies by lot)
Sequence Length
4704
Applicable Applications for anti-BTG1 antibody
Dot Blot (DB)
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility
Filtered through a 0.22 um membrane.

Quality Control

(Western blot analysis of immunized recombinant protein, using anti-BTG1 monoclonal antibody. )

Quality Control (Western blot analysis of immunized recombinant protein, using anti-BTG1 monoclonal antibody. )

Quality Control #2

(Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.)

Quality Control #2 (Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.)
Related Product Information for anti-BTG1 antibody
The BTG1 gene locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. It is a member of a family of antiproliferative genes. BTG1 expression is maximal in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. It negatively regulates cell proliferation. [NCBI Entrez Gene Summary]

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
694
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19,209 Da
NCBI Official Full Name
Homo sapiens B-cell translocation gene 1, anti-proliferative (BTG1), mRNA
NCBI Official Synonym Full Names
B-cell translocation gene 1, anti-proliferative
NCBI Official Symbol
BTG1
NCBI Protein Information
protein BTG1; B-cell translocation gene 1 protein
Protein Family
UniProt Gene Name
BTG1
UniProt Entry Name
BTG1_HUMAN

NCBI Description

This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008]

Uniprot Description

BTG1: Anti-proliferative protein. A chromosomal aberration involving BTG1 may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t(8;12)(q24;q22) with MYC. Belongs to the BTG family.

Protein type: Oncoprotein; Cell cycle regulation

Chromosomal Location of Human Ortholog: 12q22

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; enzyme binding; transcription cofactor activity; kinase binding

Biological Process: negative regulation of cell proliferation; positive regulation of angiogenesis; cell migration; positive regulation of endothelial cell differentiation; regulation of transcription, DNA-dependent; negative regulation of cell growth; positive regulation of myoblast differentiation

Research Articles on BTG1

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Product Notes

The BTG1 btg1 (Catalog #AAA120115) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse monoclonal antibody Anti-Human BTG1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BTG1 can be used in a range of immunoassay formats including, but not limited to, Dot Blot (DB). Researchers should empirically determine the suitability of the BTG1 btg1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BTG1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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