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Mouse anti-Human Brain Natriuretic Peptide, Pro, aa13-27 Monoclonal Antibody

Brain Natriuretic Peptide, Pro, NT, aa13-27 (NT-proBNP, N-terminal prohormone brain natriuretic peptide)

Reactivity
Human
Applications
Western Blot
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
Brain Natriuretic Peptide; Pro; aa13-27; Monoclonal Antibody; NT; aa13-27 (NT-proBNP; N-terminal prohormone brain natriuretic peptide); Anti -Brain Natriuretic Peptide; anti-Brain Natriuretic Peptide; aa13-27 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
7E102
Specificity
Recognizes human proBNP and NT-proBNP.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
Applicable Applications for anti-Brain Natriuretic Peptide, Pro, aa13-27 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Immunogen
Synthetic peptide corresponding to aa13-27
Hybridoma
Hybridization of Sp2/0 myeloma cells with spleen cells from Balb/c mice.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-Brain Natriuretic Peptide, Pro, aa13-27 antibody
Human brain natriuretic peptide (BNP) is a secreted protein which is a member of the natriuretic peptide family. BNP is a cardiac hormone, which is synthesized as a pro-hormone (proBNP), and is proteolytically cleaved to release a biologically active fragment (BNP), and an inactive fragment (NT-proBNP) into the circulation.

BNP is predominantly secreted from the cardiac ventricles in response to volume and pressure overload, and results in a number of biological activities including natriuresis, diuresis, vasorelaxation, and inhibition of the sympathetic nervous system. A high concentration of BNP in the bloodstream is indicative of heart failure.
Product Categories/Family for anti-Brain Natriuretic Peptide, Pro, aa13-27 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI Official Full Name
Brain natriuretic peptide

Uniprot Description

Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion ().

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Product Notes

The Brain Natriuretic Peptide, Pro, aa13-27 (Catalog #AAA6007398) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Brain Natriuretic Peptide, Pro, NT, aa13-27 (NT-proBNP, N-terminal prohormone brain natriuretic peptide) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Brain Natriuretic Peptide, Pro, aa13-27 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the Brain Natriuretic Peptide, Pro, aa13-27 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Brain Natriuretic Peptide, Pro, aa13-27, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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