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Mouse anti-Human BLVRB/biliverdin reductase B Monoclonal Antibody | anti-BLVRB antibody

Mouse anti Human BLVRB/biliverdin reductase B Monoclonal Antibody

Gene Names
BLVRB; FLR; BVRB; SDR43U1; HEL-S-10
Reactivity
Human
Applications
ELISA
Synonyms
BLVRB/biliverdin reductase B; Monoclonal Antibody; Mouse anti Human BLVRB/biliverdin reductase B Monoclonal Antibody; anti-BLVRB antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b
Sequence Length
206
Applicable Applications for anti-BLVRB antibody
ELISA (EIA)
Application Notes
ELISA: 0.5-1 mug/mL. This antibody can be used at 0.5-1 mug/mL with the appropriate secondary reagents to detect Human BLVRB. The detection limit for Human BLVRB is approximately 0.078 ng/well.
Immunogen
Recombinant Human BLVRB/biliverdin reductase B protein
Buffer
0.2 mum filtered solution in PBS with 5% trehalose
Preparation and Storage
This antibody can be stored at 2 degree C- 8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
645
Molecular Weight
22,119 Da
NCBI Official Full Name
Biliverdin reductase B (flavin reductase (NADPH))
NCBI Official Synonym Full Names
biliverdin reductase B
NCBI Official Symbol
BLVRB
NCBI Official Synonym Symbols
FLR; BVRB; SDR43U1; HEL-S-10
NCBI Protein Information
flavin reductase (NADPH)
UniProt Protein Name
Flavin reductase (NADPH)
UniProt Gene Name
BLVRB
UniProt Synonym Gene Names
FLR; BVR-B; GHBP; FLR
UniProt Entry Name
BLVRB_HUMAN

NCBI Description

The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B (EC 1.3.1.24).[supplied by OMIM, Jul 2009]

Uniprot Description

BLVRB: Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.

Protein type: Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; EC 1.3.1.24; EC 1.5.1.30; Oxidoreductase

Chromosomal Location of Human Ortholog: 19q13.1-q13.2

Cellular Component: cytoplasm; cytosol; nucleoplasm; plasma membrane

Molecular Function: biliverdin reductase activity; flavin reductase activity

Biological Process: heme catabolic process

Research Articles on BLVRB

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Product Notes

The BLVRB blvrb (Catalog #AAA2543734) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse anti Human BLVRB/biliverdin reductase B Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BLVRB/biliverdin reductase B can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 0.5-1 mug/mL. This antibody can be used at 0.5-1 mug/mL with the appropriate secondary reagents to detect Human BLVRB. The detection limit for Human BLVRB is approximately 0.078 ng/well. Researchers should empirically determine the suitability of the BLVRB blvrb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BLVRB/biliverdin reductase B, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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