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ELISA (EIA)

Mouse anti-Human Blood Group Antigen A Monoclonal Antibody | anti-CD173 antibody

Anti-Blood Group Antigen A Antibody (CD173) (HE-193)

Gene Names
ABO; GTB; NAGAT; A3GALNT; A3GALT1
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry
Purity
Protein A/G purification
Synonyms
Blood Group Antigen A; Monoclonal Antibody; Anti-Blood Group Antigen A Antibody (CD173) (HE-193); A transferase; ABO; B transferase; CD173; Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; Histo-blood group A transferase; Histo-blood group B transferase; NAGAT; anti-CD173 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgM, kappa
Clone Number
HE-193
Specificity
Monoclonal antibody to detect Blood Group Antigen A Antibody (CD173)in human samples
Purity/Purification
Protein A/G purification
Form/Format
Colorless liquid. In 10mM PBS with 0.05% BSA & 0.05% azide
Applicable Applications for anti-CD173 antibody
Agglutination, Immunofluorescence (IF), Immunohistochemistry (IHC)
Application Notes
IF: 0.5-1ug/ml
IHC: 0.5-1ug/ml
Immunogen
Mixture of erythrocytes of blood group A and glycoprotein fraction isolated from the saliva of secretors with blood group A
Positive Control
IHC: Colon carcinoma
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months

ELISA (EIA)

ELISA (EIA)

Flow Cytometry (FC/FACS)

Flow Cytometry (FC/FACS)
Related Product Information for anti-CD173 antibody
This antibody recognizes human blood group A (monofucosyl and difucosyl A antigens with chain types 1, 2, 3, 4, 5, 6) and Forssmann antigen. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
Product Categories/Family for anti-CD173 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
28
Molecular Weight
354
NCBI Official Full Name
Histo-blood group ABO system transferase
NCBI Official Synonym Full Names
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
NCBI Official Symbol
ABO
NCBI Official Synonym Symbols
GTB; NAGAT; A3GALNT; A3GALT1
NCBI Protein Information
histo-blood group ABO system transferase; ABO weak transfer; ABO A3 transferase; ABO glycosyltransferase; histo-blood group A transferase; histo-blood group B transferase; histo-blood group A2 transferase; B(A) alpha-1,3-galactosyltransferase; fucosylglyc
UniProt Protein Name
Histo-blood group ABO system transferase
UniProt Gene Name
ABO
UniProt Synonym Gene Names
A transferase; B transferase
UniProt Entry Name
BGAT_HUMAN

NCBI Description

This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

ABO: This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. Belongs to the glycosyltransferase 6 family.

Protein type: Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; EC 2.4.1.37; Membrane protein, integral; EC 2.4.1.40; Transferase

Chromosomal Location of Human Ortholog: 9q34.2

Cellular Component: integral to membrane; extracellular region

Molecular Function: metal ion binding; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity; fucosylgalactoside 3-alpha-galactosyltransferase activity

Biological Process: protein amino acid glycosylation

Disease: Blood Group, Abo System

Research Articles on CD173

Similar Products

Product Notes

The CD173 abo (Catalog #AAA847314) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Blood Group Antigen An Antibody (CD173) (HE-193) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Blood Group Antigen A can be used in a range of immunoassay formats including, but not limited to, Agglutination, Immunofluorescence (IF), Immunohistochemistry (IHC). IF: 0.5-1ug/ml IHC: 0.5-1ug/ml. Researchers should empirically determine the suitability of the CD173 abo for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Blood Group Antigen A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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