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Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant BIN3 protein (Right) or empty vector (Left) detected with BIN3 antibody)

Mouse BIN3 Monoclonal Antibody | anti-BIN3 antibody

BIN3 antibody

Applications
Flow Cytometry, Functional Assay, Western Blot
Purity
BIN3 antibody was purified by affinity chromatography.
Synonyms
BIN3; Monoclonal Antibody; BIN3 antibody; Monoclonal BIN3; Anti-BIN3; Bridging integrator 3; MGC14978; BIN 3; BIN-3; anti-BIN3 antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4A6
Purity/Purification
BIN3 antibody was purified by affinity chromatography.
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
500 ug-1 mg/ml (varies by lot)
Sequence Length
253
Applicable Applications for anti-BIN3 antibody
Flow Cytometry (FC/FACS), Western Blot (WB)
Application Notes
FC: 1:100
WB: 1:500
Biological Significance
BIN3 is a member of the BAR domain protein family. The encoded protein is comprised solely of a BARdomain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellulartransport, and a diverse set of other processes.
Cross-Reactivity
Human
Immunogen
BIN3 antibody was raised in mouse using a full length recombinant protein of human BIN3 (NP_061158) produced in HEK293T cells, as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Western Blot (WB)

(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant BIN3 protein (Right) or empty vector (Left) detected with BIN3 antibody)

Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant BIN3 protein (Right) or empty vector (Left) detected with BIN3 antibody)
Related Product Information for anti-BIN3 antibody
Mouse monoclonal BIN3 antibody
Product Categories/Family for anti-BIN3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23,218 Da
NCBI Official Full Name
bridging integrator 3
NCBI Official Synonym Full Names
bridging integrator 3
NCBI Official Symbol
BIN3
NCBI Protein Information
bridging integrator 3
UniProt Protein Name
Bridging integrator 3
Protein Family
UniProt Gene Name
BIN3
UniProt Entry Name
BIN3_HUMAN

NCBI Description

The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes. [provided by RefSeq, Jul 2008]

Uniprot Description

BIN3: Involved in cytokinesis and septation where it has a role in the localization of F-actin. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 8p21.3

Cellular Component: cytoplasm; actin filament

Molecular Function: protein binding; cytoskeletal adaptor activity

Biological Process: barrier septum formation; unidimensional cell growth; protein localization; cytokinesis; actin filament organization; skeletal muscle fiber development; myoblast migration involved in skeletal muscle regeneration

Research Articles on BIN3

Similar Products

Product Notes

The BIN3 bin3 (Catalog #AAA831381) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's BIN3 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Western Blot (WB). FC: 1:100 WB: 1:500. Researchers should empirically determine the suitability of the BIN3 bin3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BIN3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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