Immunohistochemistry (IHC)
(Anti-beta-HCG antibody (monoclonal), MBS175063, IHC(P)IHC(P): Human Placenta Tissue )
Mouse anti-Human beta-HCG Monoclonal Antibody | anti-CGB antibody
Anti-beta-HCG antibody (monoclonal)
Immunohistochemistry (IHC)
(Anti-beta-HCG antibody (monoclonal), MBS175063, IHC(P)IHC(P): Human Placenta Tissue )
Immunohistochemistry (IHC)
(Anti-beta-HCG antibody (monoclonal), MBS175063, IHC(P)IHC(P): Human Placenta Tissue )
Background: beta-HCG(beta-Human Chorionic Gonadotropin), also termed as Chorionic Gonadotropin, Beta Chain(CGB). It is encoded by a multigene cluster composed of six homologous sequences. And in the family of beta-containing glycoprotein hormones, beta-HCG is unique in that it contains an extension of 29 amino acids at its COOH end. beta-HCG is mapped to 19q13.32 and expressed in trophoblast and various malignant tumors promotes cellular motility in vivo. beta-HCG has a novel function in uterine adaptation to early pregnancy as well as in tumor development and underline the importance of HCG as an as yet unrecognized angiogenic factor.
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 8 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]
Uniprot Description
CGB: Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. Belongs to the glycoprotein hormones subunit beta family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide; Inhibitor
Chromosomal Location of Human Ortholog: 19q13.32
Cellular Component: extracellular region
Molecular Function: hormone activity
Biological Process: cellular protein metabolic process; cell-cell signaling; apoptosis; peptide hormone processing; female gamete generation; signal transduction
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Product Notes
The CGB cgb (Catalog #AAA175063) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-beta-HCG antibody (monoclonal) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's beta-HCG can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the CGB cgb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "beta-HCG, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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