Mouse Bacillus anthracis Lethal Factor Antigen Monoclonal Antibody
Bacillus anthracis Lethal Factor Antigen Monoclonal Antibody
Applications
ELISA, Immunoblot, Western Blot
Synonyms
Bacillus anthracis Lethal Factor Antigen; Monoclonal Antibody; Bacillus anthracis Lethal Factor Antigen Monoclonal Antibody; anti-Bacillus anthracis Lethal Factor Antigen antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
106
Specificity
Bacillus anthracis Lethal Factor Antigen [These monoclonal antibodies recognize different epitopes of B. anthracis Lethal Factor. They do not cross-react with B. anthracis Protective Antigen, Edema Factor, or spore/vegetative surface antigens.]
These antibodies recognize different epitopes of B. anthracis LF. They do not cross-react with B. anthracis PA, EF, or spore/vegetative surface antigens.
These antibodies recognize different epitopes of B. anthracis LF. They do not cross-react with B. anthracis PA, EF, or spore/vegetative surface antigens.
Form/Format
200 ug purified antibody in PBS, pH 7.4.
Applicable Applications for anti-Bacillus anthracis Lethal Factor Antigen antibody
ELISA, Immunoblot
Application Notes
Immunoblotting: use at 5 ug/ml.
Sandwich ELISA: use coating antibody at 5 ug/ml
Sandwich ELISA: use coating antibody at 5 ug/ml
Antigen
Purified B. anthracis Lethal Factor (82 kD).
Preservatives
0.1% NaN3
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
These antibodies are stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Related Product Information for anti-Bacillus anthracis Lethal Factor Antigen antibody
Anthrax toxin produced by Bacillus anthracis is composed of three proteins: Protective Antigen (PA), Edema Factor (EF), and Lethal Factor (LF). Toxicity requires the assembly of all three of these proteins, and this process is initiated when PA binds to the cell surface ATR (anthrax toxin receptor). After binding, PA is enzymaticaly cleaved to yield a 63 kD fragment which then binds EF and LF, and the complex is internalized. LF is a protease and cleaves enzymes of the MAPKK (mitogen-activated protein kinase kinase) family.
Product Categories/Family for anti-Bacillus anthracis Lethal Factor Antigen antibody
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Product Notes
The Bacillus anthracis Lethal Factor Antigen (Catalog #AAA190055) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Bacillus anthracis Lethal Factor Antigen can be used in a range of immunoassay formats including, but not limited to, ELISA, Immunoblot. Immunoblotting: use at 5 ug/ml. Sandwich ELISA: use coating antibody at 5 ug/ml. Researchers should empirically determine the suitability of the Bacillus anthracis Lethal Factor Antigen for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bacillus anthracis Lethal Factor Antigen, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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