Mouse ASCL3 Monoclonal Antibody | anti-ASCL3 antibody
ASCL3 (Achaete-scute Complex Homolog 3 (Drosophila), HASH3, SGN1, bHLHa42) (MaxLight 405)
NCBI and Uniprot Product Information
NCBI Description
Basic helix-loop-helix transcription factors, such as ASCL3, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]).[supplied by OMIM, Mar 2008]
Uniprot Description
ASCL3: Transcriptional repressor. Inhibits myogenesis.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 11p15.3
Cellular Component: transcription factor complex; nucleus
Molecular Function: protein dimerization activity; DNA binding
Biological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent