Mouse Arginase I Monoclonal Antibody
Arginase I, Human, mAb D1.2
Reactivity
Human, Sheep, Horse (Weak)
Applications
Flow Cytometry, Functional Assay, Western Blot
Synonyms
Arginase I; Monoclonal Antibody; Human; mAb D1.2; anti-Arginase I antibody
Host
Mouse
Reactivity
Human, Sheep, Horse (Weak)
Clonality
Monoclonal
Isotype
IgG1
Clone Number
D1.2
Form/Format
1 ml (100 ug/ml) 0.2 um filtered antibody solution in PBS, containing 0.1% bovine serum albumin and 0.02% sodium azide.
For unit size 0.5 mg or larger: PBS only (concentration< 0.5mg/ml)
For unit size 0.5 mg or larger: PBS only (concentration< 0.5mg/ml)
Applicable Applications for anti-Arginase I antibody
Flow Cytometry (FC/FACS), Immuno Assay (IA), Western Blot (WB)
Application Notes
WB: A reduced sample treatment and SDS-Page was used. The band size is 40 kDa
Immunogen
Peptide D14967-1-1t/m6
Preparation and Storage
Store at 4 degree C. Under recommended storage conditions, product is stable for at least one year.
Related Product Information for anti-Arginase I antibody
Monoclonal antibody D1.2 reacts specifically with Arginase I, the final enzyme in the urea cycle, which is responsible for the hydrolysis of arginine to urea and ornithine. The highest concentration of the enzyme is present in the liver in which the bulk of ureagenesis occurs. Two types of arginases are known: Arginase I and II. The cytosolic enzyme found primarily in liver is Arginase I, a 35 kD protein that circulates as trimer. Arginase II is exclusively located in the mitochondrion. Arginase I is next to the liver in man also expressed by mature fetal and adult red blood cells and activated monocytic cells. During inflammation induction of Arginase I by inflammatory cytokines in monocytic cells is considered to lead to a local depletion of arginine resulting in a microenvironment that prevents nitric oxide production and arginine dependent T cell function. Arginase II is expressed by kidney, nucleated red blood cells, brain, spinal cord, gastro-intestinal tract, mammary gland and prostate. Enhanced circulating Arginase I levels have been reported after surgery, following haemorrhage and in asthmatic patients. Measurement of circulating Arginase I has been used experimentally as rapid marker for liver injury.
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Product Notes
The Arginase I (Catalog #AAA584770) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Arginase I, Human, mAb D1.2 reacts with Human, Sheep, Horse (Weak) and may cross-react with other species as described in the data sheet. AAA Biotech's Arginase I can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immuno Assay (IA), Western Blot (WB). WB: A reduced sample treatment and SDS-Page was used. The band size is 40 kDa. Researchers should empirically determine the suitability of the Arginase I for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Arginase I, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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