Mouse ApoA-I Monoclonal Antibody | anti-ApoA-I antibody

ApoA-I Antibody

Cat. Num. AAA856157

• Gene Names: APOA1; apo(a)
• Synonyms: ApoA-I; Monoclonal Antibody; ApoA-I Antibody; anti-ApoA-I antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Specificity: Anti-ApoA-I recognizes recombinant protein ApoA-I.
• Form/Format: Each vial contains 100 ug IgG in 100 ul of citrate-tris-HCl buffer pH7.0 with 0.02% Proclin 300.
• Sequence Length: 267

• Immunogen: Recombinant protein corresponding to full length ApoA-I.
• Preparation and Storage: The antibody may be stored at-20 degree C for one year in its original formulation. Additionally, antibody may be stored at 2 degree C to 8 degree C for up to 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles of the diluted antibody.

Testing Data

Related Product Information for anti-ApoA-I antibody

Purified mouse monoclonal antibody generated using E Coli expressed recombinant protein ApoA-I as immunogen.

Product Categories/Family for anti-ApoA-I antibody

Plant antibody

NCBI and Uniprot Product Information

• NCBI GI #: 4557321
• NCBI GeneID: 335
• NCBI Accession #: NP_000030.1
• NCBI GenBank Nucleotide #: NM_000039.2
• UniProt Accession #: P02647; Q6LDN9; Q6Q785; Q9UCS8; Q9UCT8; A8K866
• Molecular Weight: 30,778 Da
• NCBI Official Full Name: apolipoprotein A-I isoform 1 preproprotein
• NCBI Official Synonym Full Names: apolipoprotein A1
• NCBI Official Symbol: APOA1
• NCBI Official Synonym Symbols: apo(a)
• NCBI Protein Information: apolipoprotein A-I
• UniProt Protein Name: Apolipoprotein A-I
• UniProt Gene Name: APOA1
• UniProt Synonym Gene Names: Apo-AI; ApoA-I; ProapoA-I

NCBI Description

This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015]

Uniprot Description

Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.