Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (Western Blot; Sample: Human Lung lysatePrimary Ab: 1.5ug/ml Mouse Anti-Human ANXA3 AntibodySecond Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody )

Mouse anti-Human Annexin A3 (ANXA3) Monoclonal Antibody | anti-ANXA3 antibody

Monoclonal Antibody to Annexin A3 (ANXA3)

Gene Names
ANXA3; ANX3
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
Purity
Protein A + Protein G Affinity Chromatography
Synonyms
Annexin A3 (ANXA3); Monoclonal Antibody; Monoclonal Antibody to Annexin A3 (ANXA3); ANX-A3; ANX3; PAP-III; 35-alpha calcimedin; Inositol 1; 2-cyclic phosphate 2-phosphohydrolase; Lipocortin III; Placental anticoagulant protein III; anti-ANXA3 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b Kappa
Clone Number
C5
Specificity
The antibody is a mouse monoclonal antibody raised against ANXA3. It has been selected for its ability to recognize ANXA3 in immunohistochemical staining and western blotting.
Purity/Purification
Protein A + Protein G Affinity Chromatography
Form/Format
Liquid; 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence
Trp190~Glu312
Applicable Applications for anti-ANXA3 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes
WB: 0.2-2ug/mL; 1:500-5000
IHC: 5-20ug/mL; 1:50-200
Immunogen Sequence
Trp190~Glu312
Cross Reactivity
Human
Conjugation
None
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Western Blot (WB)

(Western Blot; Sample: Human Lung lysatePrimary Ab: 1.5ug/ml Mouse Anti-Human ANXA3 AntibodySecond Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody )

Western Blot (WB) (Western Blot; Sample: Human Lung lysatePrimary Ab: 1.5ug/ml Mouse Anti-Human ANXA3 AntibodySecond Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody )

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Human Liver Tissue; Primary Ab: 10ug/ml Mouse Anti-Human ANXA3 Antibody Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody )

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Human Liver Tissue; Primary Ab: 10ug/ml Mouse Anti-Human ANXA3 Antibody Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody )

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Human Kidney Tissue; Primary Ab: 10ug/ml Mouse Anti-Human ANXA3 AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody )

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Human Kidney Tissue; Primary Ab: 10ug/ml Mouse Anti-Human ANXA3 AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody )
Product Categories/Family for anti-ANXA3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
306
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
36,375 Da
NCBI Official Full Name
annexin A3
NCBI Official Synonym Full Names
annexin A3
NCBI Official Symbol
ANXA3
NCBI Official Synonym Symbols
ANX3
NCBI Protein Information
annexin A3; 35-alpha calcimedin; Annexin III (lipocortin III); PAP-III; annexin III (lipocortin III, 1,2-cyclic-inositol-phosphate phosphodiesterase, placental anticoagulant protein III, calcimedin 35-alpha); annexin-3; inositol 1,2-cyclic phosphate 2-pho
UniProt Protein Name
Annexin A3
Protein Family
UniProt Gene Name
ANXA3
UniProt Synonym Gene Names
ANX3; PAP-III
UniProt Entry Name
ANXA3_HUMAN

NCBI Description

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation. [provided by RefSeq, Jul 2008]

Uniprot Description

ANXA3: a calcium/phospholipid-binding protein and inhibitor of phospholipase A2, Possesses anti-coagulant properties. Cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 4q21.21

Cellular Component: specific granule; phagocytic vesicle membrane; membrane; cytoplasm; plasma membrane

Molecular Function: calcium-dependent phospholipid binding; phospholipase A2 inhibitor activity; calcium ion binding; calcium-dependent protein binding

Biological Process: positive regulation of angiogenesis; negative regulation of catalytic activity; neutrophil degranulation; defense response to bacterium; positive regulation of transcription factor activity; phagocytosis

Research Articles on ANXA3

Similar Products

Product Notes

The ANXA3 anxa3 (Catalog #AAA2111692) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Antibody to Annexin A3 (ANXA3) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Annexin A3 (ANXA3) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). WB: 0.2-2ug/mL; 1:500-5000 IHC: 5-20ug/mL; 1:50-200. Researchers should empirically determine the suitability of the ANXA3 anxa3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Trp190~Glu 312. It is sometimes possible for the material contained within the vial of "Annexin A3 (ANXA3), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.