Mouse Angiotensin Converting Enzyme Human Monoclonal Antibody

Angiotensin Converting Enzyme (ACE) Monoclonal Antibody

Cat. Num. AAA190018

• Applications: ELISA, Flow Cytometry, Immunohistochemistry
• Synonyms: Angiotensin Converting Enzyme Human; Monoclonal Antibody; Angiotensin Converting Enzyme (ACE) Monoclonal Antibody; Anti-Angiotensin Converting Enzyme Human; Angiotensin Converting Enzyme; anti-Angiotensin Converting Enzyme Human antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgM
• Specificity: Anti-Angiotensin Converting Enzyme Human [Human, bovine, mouse ACE and endothelial cells.]; This antibody reacts specifically with human, bovine, and murine ACE and with ACE-positive endothelial cells.
• Form/Format: 100 ug purified antibody in PBS, pH 7.4. Purified by precipitation with 6% polyethylene glycol (PEG).
• Concentration: 0.7 mg/ml (varies by lot)

• Applicable Applications for anti-Angiotensin Converting Enzyme Human antibody: ELISA, Flow Cytometry, Immunohistochemistry
• Application Notes: This antibody may be used in ELISA, immunohistochemistry, and flow cytometry for detection of ACE or ACE-positive cells. Other applications are under investigation.
• Antigen: Angiotensin converting enzyme purified from rat lung.
• Appearance: Clear liquid
• Stabilizer: None
• Preservatives: None. Available on request.
• Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
• Preparation and Storage: These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

Product Categories/Family for anti-Angiotensin Converting Enzyme Human antibody

Enzyme and Enzyme Inhibitor Antibodies

References

Auerbach, R. et al. (1982) Proc Natl Acad Sci USA 79: 7891.

NCBI and Uniprot Product Information

• NCBI GI #: 29788982
• NCBI Official Full Name: angiotensin-converting enzyme

NCBI Description

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010]