Testing Data
(Immunoperoxidase of monoclonal antibody to AKT1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml])
Mouse AKT1 Monoclonal Antibody | anti-AKT1 antibody
AKT1 (v-akt murine Thymoma Viral Oncogene Homolog 1, AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA) (PE)
Testing Data
(Immunoperoxidase of monoclonal antibody to AKT1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml])
Testing Data
(Immunoperoxidase of monoclonal antibody to AKT1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml])
Immunohistochemistry (IHC)
(Immunoperoxidase of monoclonal antibody to AKT1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml])
Immunohistochemistry (IHC)
(Immunoperoxidase of monoclonal antibody to AKT1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml])
Western Blot (WB)
(AKT1 monoclonal antibody (M06), clone 2H1 Western Blot analysis of AKT1 expression in HL-60 (Cat # L014V1).)
Western Blot (WB)
(AKT1 monoclonal antibody (M06), clone 2H1 Western Blot analysis of AKT1 expression in HL-60 (Cat # L014V1).)
Testing Data
(Detection limit for recombinant GST tagged AKT1 is approximately 3ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged AKT1 is approximately 3ng/ml as a capture antibody.)
NCBI and Uniprot Product Information
NCBI Description
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]
Research Articles on AKT1
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Product Notes
The AKT1 (Catalog #AAA6184007) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's AKT1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the AKT1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AKT1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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