Immunofluorescence (IF)
(Immunofluorescent staining of AID knock-out (top) or wild type (bottom) mouse intestinal Peyer's patches with AID antibody (MBS837837))
Sheep anti-Human AID Monoclonal Antibody | anti-AID antibody
AID antibody (biotin)
Reactivity
Human
Applications
Immunohistochemistry, Immunohistochemistry, Western Blot
Synonyms
AID; Monoclonal Antibody; AID antibody (biotin); Monoclonal AID; Anti-AID; Activation-induced deaminase; Aicda; Aid; Activation-induced cytidine deaminase; Arp2; Cytidine aminohydrolase; anti-AID antibody
Host
Sheep
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a kappa
Specificity
Human
Form/Format
Supplied in an aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration
500 ug/ml (varies by lot)
Applicable Applications for anti-AID antibody
Immunohistochemistry (IHC), Immunohistochemistry (IHC) Formalin, Western Blot (WB)
Biological Significance
AID is a 24 kDa RNA-editing enzyme that converts cytosine into uracil. It plays a critical role during B cell development, specifically in somatic hypermutation (SHM) and immunoglobulin class switch recombination (CSR). Changes in levels of AID expression typically present with disease. For example, mutations in AID are found in Hyper-IgM Syndrome (type 2), a disease form without opportunistic infections, while overexpression correlates with poor prognosis in chronic lymphocytic leukemia/small lymphocytic lymphoma.
Cross-Reactivity
Human, Mouse
Tag/Conjugate
Biotin
Preparation and Storage
Store at 2-8 degree C
Immunofluorescence (IF)
(Immunofluorescent staining of AID knock-out (top) or wild type (bottom) mouse intestinal Peyer's patches with AID antibody (MBS837837))
Immunofluorescence (IF)
(Immunofluorescent staining of AID knock-out (top) or wild type (bottom) mouse intestinal Peyer's patches with AID antibody (MBS837837))
Immunofluorescence (IF)
(Immunofluorescent staining of AID knock-out (top) or wild type (bottom) mouse intestinal Peyer's patches with AID antibody (MBS837837))
Immunofluorescence (IF)
(Immunofluorescent staining of AID knock-out (top) or wild type (bottom) mouse intestinal Peyer's patches with AID antibody (MBS837837))
Related Product Information for anti-AID antibody
Rat monoclonal AID antibody (biotin)
Product Categories/Family for anti-AID antibody
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Product Notes
The AID (Catalog #AAA837837) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. The AID antibody (biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AID can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunohistochemistry (IHC) Formalin, Western Blot (WB). Researchers should empirically determine the suitability of the AID for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AID, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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