Mouse AHCY Monoclonal Antibody | anti-AHCY antibody

AHCY (S-adenosylhomocysteine Hydrolase, SAHH) (FITC)

Cat. Num. AAA6175181

• Gene Names: AHCY; SAHH; adoHcyase
• Applications: ELISA, Western Blot
• Purity: Purified
• Synonyms: AHCY; Monoclonal Antibody; AHCY (S-adenosylhomocysteine Hydrolase; SAHH) (FITC); S-adenosylhomocysteine Hydrolase; SAHH; anti-AHCY antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1,k
• Clone Number: M2
• Specificity: Recognizes AHCY.
• Purity/Purification: Purified
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
• Sequence Length: 432

• Applicable Applications for anti-AHCY antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: AHCY (AAH11606, 1aa-432aa) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD.
• Conjugate: FITC
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer.; ; FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(AHCY monoclonal antibody (M09), clone M2. Western Blot analysis of AHCY expression in A-549 (Cat # L025V1).)

Western Blot (WB)

(AHCY monoclonal antibody (M09), clone M2. Western Blot analysis of AHCY expression in different cell lines.)

Related Product Information for anti-AHCY antibody

S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Product Categories/Family for anti-AHCY antibody

Antibodies; Enzymes

References

1. Identification of S100A8 and S100A9 as Serological Markers for Colorectal Cancer. Kim HJ, Kang HJ, Lee H, Lee ST, Yu MH, Kim H, Lee C.J Proteome Res. 2009 Mar;8(3):1368-79.

NCBI and Uniprot Product Information

• NCBI GI #: 15079562
• NCBI GeneID: 191
• NCBI Official Full Name: S-adenosylhomocysteine hydrolase
• NCBI Official Synonym Full Names: adenosylhomocysteinase
• NCBI Official Symbol: AHCY
• NCBI Official Synonym Symbols: SAHH; adoHcyase
• NCBI Protein Information: adenosylhomocysteinase
• Protein Family: Adenosylhomocysteinase

NCBI Description

S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]