Mouse ADRM1 Monoclonal Antibody | anti-ADRM1 antibody

ADRM1 (Adhesion regulating Molecule 1, ARM1, GP110, MGC29536, Rpn13) (Biotin)

Cat. Num. AAA6172662

• Gene Names: ADRM1; ARM1; ARM-1; GP110
• Applications: Western Blot
• Purity: Purified
• Synonyms: ADRM1; Monoclonal Antibody; ADRM1 (Adhesion regulating Molecule 1; ARM1; GP110; MGC29536; Rpn13) (Biotin); Adhesion regulating Molecule 1; Rpn13; anti-ADRM1 antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2b,k
• Clone Number: 3D11
• Specificity: Recognizes ADRM1.
• Purity/Purification: Purified
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-ADRM1 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: ADRM1 (AAH17245.1, 18aa-407aa) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD.
• Conjugate: Biotin
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ADRM1 monoclonal antibody (M02), clone 3D11. Western Blot analysis of ADRM1 expression in HeLa (Cat # L013V1).)

Western Blot (WB)

(Western Blot analysis of ADRM1 expression in transfected 293T cell line by ADRM1 monoclonal antibody (M02), clone 3D11.Lane 1: ADRM1 transfected lysate (42.2 KDa).Lane 2: Non-transfected lysate.)

Testing Data

(Detection limit for recombinant GST tagged ADRM1 is 0.03 ng/ml as a capture antibody.)

Related Product Information for anti-ADRM1 antibody

The protein encoded by this gene is an integral plasma membrane protein which promotes cell adhesion. The encoded protein is thought to undergo O-linked glycosylation. Expression of this gene has been shown to be induced by gamma interferon in some cancer cells. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]

Product Categories/Family for anti-ADRM1 antibody

Antibodies; Ubiquitin

NCBI and Uniprot Product Information

• NCBI GI #: 16878071
• NCBI GeneID: 11047
• Molecular Weight: 42,153 Da
• NCBI Official Full Name: Adhesion regulating molecule 1
• NCBI Official Synonym Full Names: adhesion regulating molecule 1
• NCBI Official Symbol: ADRM1
• NCBI Official Synonym Symbols: ARM1; ARM-1; GP110
• NCBI Protein Information: proteasomal ubiquitin receptor ADRM1; rpn13 homolog; M(r) 110,000 surface antigen; 110 kDa cell membrane glycoprotein; proteasome regulatory particle non-ATPase 13

NCBI Description

This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]