Western Blot
(Western Blot analysis using ACY3 antibodyWestern Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant ACY3 protein (Right) or empty vector (Left) detected with ACY3 antibody)
Mouse ACY3 Monoclonal Antibody | anti-ACY3 antibody
ACY3 antibody
Gene Names
ACY3; ACY-3; HCBP1
Applications
Western Blot
Purity
ACY3 antibody was purified by affinity chromatography.
Synonyms
ACY3; Monoclonal Antibody; ACY3 antibody; Monoclonal ACY3; Anti-ACY3; ACY-3; ACY 3; HCBP1; Aminoacylase-3; anti-ACY3 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4C1
Purity/Purification
ACY3 antibody was purified by affinity chromatography.
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
500 ug-1 mg/ml (varies by lot)
Sequence Length
319
Applicable Applications for anti-ACY3 antibody
Western Blot (WB)
Application Notes
WB: 1:200-500
Biological Significance
Aspartoacylase 3, also known as ACY3, is a member of the Aspartoacylase subfamily. It plays an important role in deacetylating mercapturic acids in kidney proximal tubules. ACY3 localizes to the cytoplasm of S2 and S3 proximal tubules and to the apical domain of S1 proximal tubules. ACY3 protein is also expressed at low levels in stomach, testis, heart, brain, lung and liver, and may function as an HCV (Hepatitis C virus) core binding protein.
Cross-Reactivity
Human
Immunogen
ACY3 antibody was raised in mouse using a full length recombinant protein of human ACY3 (NP_542389) produced in HEK293T cells, as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Western Blot
(Western Blot analysis using ACY3 antibodyWestern Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant ACY3 protein (Right) or empty vector (Left) detected with ACY3 antibody)
Western Blot
(Western Blot analysis using ACY3 antibodyWestern Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant ACY3 protein (Right) or empty vector (Left) detected with ACY3 antibody)
Related Product Information for anti-ACY3 antibody
Mouse monoclonal ACY3 antibody
Product Categories/Family for anti-ACY3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,241 Da
NCBI Official Full Name
N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)
NCBI Official Synonym Full Names
aminoacylase 3
NCBI Official Symbol
ACY3
NCBI Official Synonym Symbols
ACY-3; HCBP1
NCBI Protein Information
N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)
UniProt Protein Name
N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)
Protein Family
UniProt Gene Name
ACY3
UniProt Synonym Gene Names
ASPA2; ACY-3; HCBP1; HCV core-binding protein 1
UniProt Entry Name
ACY3_HUMAN
Uniprot Description
ACY3: Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Belongs to the AspA/AstE family. Aspartoacylase subfamily.
Protein type: Amino Acid Metabolism - histidine; EC 3.5.1.114; Amino Acid Metabolism - alanine, aspartate and glutamate; Hydrolase
Chromosomal Location of Human Ortholog: 11q13.2
Cellular Component: apical plasma membrane; cytosol
Molecular Function: identical protein binding; metal ion binding; hydrolase activity, acting on ester bonds; aminoacylase activity
Biological Process: viral reproduction; xenobiotic metabolic process
Research Articles on ACY3
Similar Products
Product Notes
The ACY3 acy3 (Catalog #AAA831354) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ACY3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:200-500. Researchers should empirically determine the suitability of the ACY3 acy3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACY3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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