Rabbit anti-Human Acidic Cytokeratin Monoclonal Antibody | anti-KRT77 antibody
Acidic Cytokeratin Recombinant monoclonal antibody (RMAK1-1)
Gene Names
KRT77; K1B; KRT1B
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry
Purity
Protein A affinity purified
Synonyms
Acidic Cytokeratin; Monoclonal Antibody; Acidic Cytokeratin Recombinant monoclonal antibody (RMAK1-1); anti-KRT77 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG kappa
Clone Number
RMAK1-1
Purity/Purification
Protein A affinity purified
Form/Format
Liquid. In 1X PBS containing 0.1mg/ml BSA (US sourced) and 0.05% sodium azide
Applicable Applications for anti-KRT77 antibody
Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin
Antibody Type
Recombinant antibody
Immunogen
An amino acid sequence common to acidic/type I keratins
Preparation and Storage
For long term storage, store at 4 degree C
Shipping: Shipped on Blue Ice
Shipping: Shipped on Blue Ice
Related Product Information for anti-KRT77 antibody
There are two types of cytokeratins/keratins/CKs: the acidic type I cytokeratins and the basic or neutral type II cytokeratins. The subsets of cytokeratins which an epithelial cell expresses depends mainly on the type of epithelium, the moment in the course of terminal differentiation and the stage of development. Thus this specific keratin fingerprint allows the classification of all epithelia upon their keratin expression profile. Furthermore this applies also to the malignant counterparts of the epithelia (carcinomas), as the keratin profile tends to remain constant when an epithelium undergoes malignant transformation. The main clinical implication is that the study of the keratin profile by immunohistochemistry techniques is a tool of immense value widely used for tumor test and characterization in surgical pathology.
Product Categories/Family for anti-KRT77 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40-56.5kDa
NCBI Official Full Name
keratin, type II cytoskeletal 1b
NCBI Official Synonym Full Names
keratin 77
NCBI Official Symbol
KRT77
NCBI Official Synonym Symbols
K1B; KRT1B
NCBI Protein Information
keratin, type II cytoskeletal 1b
UniProt Protein Name
Keratin, type II cytoskeletal 1b
Protein Family
UniProt Gene Name
KRT77
UniProt Synonym Gene Names
KRT1B; CK-1B; K77
UniProt Entry Name
K2C1B_HUMAN
NCBI Description
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in the skin and eccrine sweat glands. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]
Uniprot Description
K77: Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in the skin and eccrine sweat glands. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 12q13.13
Cellular Component: cytoskeleton
Research Articles on KRT77
Similar Products
Product Notes
The KRT77 krt77 (Catalog #AAA566844) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Acidic Cytokeratin Recombinant monoclonal antibody (RMAK1-1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Acidic Cytokeratin can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the KRT77 krt77 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Acidic Cytokeratin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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