Western Blot (WB)
(ABO Antibody (N-term)(Ascites) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ABO antibody detected the ABO protein (arrow).)
Mouse anti-Human ABO Monoclonal Antibody | anti-ABO antibody
ABO Antibody (N-term) (Ascites)
Western Blot (WB)
(ABO Antibody (N-term)(Ascites) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ABO antibody detected the ABO protein (arrow).)
Western Blot (WB)
(ABO Antibody (N-term)(Ascites) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ABO antibody detected the ABO protein (arrow).)
blood group system, ABO. Which allele is present in an individual
determines the blood group. The 'O' blood group is caused by a
deletion of guanine-258 near the N-terminus of the protein which
results in a frameshift and translation of an almost entirely
different protein. Individuals with the A, B, and AB alleles
express glycosyltransferase activities that convert the H antigen
into the A or B antigen. Other minor alleles have been found for
this gene.
Seltsam, A., et al. Transfusion 47(12):2330-2335(2007)
Twu, Y.C., et al. Transfusion 46(11):1988-1996(2006)
Jenkins, P.V., et al. Transfusion 46(10):1836-1844(2006)
Roubinet, F., et al. Transfusion 44(5):707-715(2004)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
ABO: This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. Belongs to the glycosyltransferase 6 family.
Protein type: Transferase; EC 2.4.1.37; EC 2.4.1.40; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Membrane protein, integral
Chromosomal Location of Human Ortholog: 9q34.2
Cellular Component: integral to membrane; extracellular region
Molecular Function: metal ion binding; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity; fucosylgalactoside 3-alpha-galactosyltransferase activity
Biological Process: protein amino acid glycosylation
Disease: Blood Group, Abo System
Research Articles on ABO
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Product Notes
The ABO abo (Catalog #AAA9200353) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 41-68. The ABO Antibody (N-term) (Ascites) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ABO can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:200~6400. Researchers should empirically determine the suitability of the ABO abo for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ABO, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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