Monkey TL1A ELISA Kit | TL1A elisa kit

Monkey TL1A (Tumor Necrosis Factor Related Ligand 1A) ELISA Kit

Cat. Num. AAA2501970

• Gene Names: TNFSF15; TL1; TL1A; VEGI; VEGI192A
• Reactivity: Monkey
• Synonyms: TL1A; Monkey TL1A (Tumor Necrosis Factor Related Ligand 1A) ELISA Kit; TL1A elisa kit

• Reactivity: Monkey
• Specificity: This kit recognizes Monkey TL1A in samples. No Significant cross-reactivity or interference between Monkey TL1A and analogues was observed.
• Sequence Length: 251

• Samples: Serum, Plasma, Biological Fluids
• Assay Type: Sandwich
• Detection Range: 0.156-10ng/mL
• Sensitivity: Min: 0.094ng/mL; Max: 10ng/mL
• Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Monkey TL1A were tested 20 times on one plate, respectively.
• Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Monkey TL1A were tested on 3 different plates, 20 replicates in each plate.
• Preparation and Storage: Store at 4 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for TL1A elisa kit

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Monkey TL1A concentrations in serum, plasma and other biological fluids.

NCBI and Uniprot Product Information

• NCBI GI #: 23510445
• NCBI GeneID: 9966
• NCBI Accession #: NP_005109.2
• NCBI GenBank Nucleotide #: NM_005118.3
• UniProt Accession #: O95150; Q3SX69; Q5VJK8; Q5VWH1; Q8NFE9
• Molecular Weight: 20,131 Da
• NCBI Official Full Name: tumor necrosis factor ligand superfamily member 15 isoform VEGI-251
• NCBI Official Synonym Full Names: tumor necrosis factor (ligand) superfamily, member 15
• NCBI Official Symbol: TNFSF15
• NCBI Official Synonym Symbols: TL1; TL1A; VEGI; VEGI192A
• NCBI Protein Information: tumor necrosis factor ligand superfamily member 15; TNF ligand-related molecule 1; TNF superfamily ligand TL1A; vascular endothelial cell growth inhibitor; vascular endothelial growth inhibitor-192A
• UniProt Protein Name: Tumor necrosis factor ligand superfamily member 15
• UniProt Gene Name: TNFSF15
• UniProt Synonym Gene Names: TL1; VEGI
• UniProt Entry Name: TNF15_HUMAN

NCBI Description

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]

Uniprot Description

TNFSF15: Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. Belongs to the tumor necrosis factor family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Cytokine; Membrane protein, integral

Chromosomal Location of Human Ortholog: 9q32

Cellular Component: extracellular space; integral to plasma membrane; plasma membrane; integral to membrane

Molecular Function: death receptor binding; cytokine activity; tumor necrosis factor receptor binding; receptor binding

Biological Process: caspase activation; cytokine metabolic process; activation of NF-kappaB-inducing kinase; immune response; signal transduction; positive regulation of cytokine secretion