Uniprot Description
AMICA1: an adhesion molecule that may function in the migration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells. Up-regulated upon retinoic acid, Me2SO and PMA treatment in differentiating myeloid leukemia cells. Three alternatively spliced isoforms have been described.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 11q23.3
Cellular Component: integral to membrane; plasma membrane; tight junction
Molecular Function: cell adhesion molecule binding; integrin binding; protein homodimerization activity
Biological Process: blood coagulation; gamma-delta T cell activation; heterophilic cell adhesion; leukocyte migration; neutrophil chemotaxis; positive regulation of epithelial cell proliferation involved in wound healing; regulation of immune response
Product Notes
The Monkey AMICA1 amica1 (Catalog #
AAA9343618) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9343618 ELISA Kit recognizes Monkey AMICA1.
It is sometimes possible for the material contained within the vial of
"Junctional Adhesion Molecule-Like (AMICA1), ELISA Kit" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a
product from AAA Biotech, you
are explicitly certifying that said products will be properly tested and used in line with
industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech
cannot be held
responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any
aspect of this datasheet at
any time and without notice. It is the responsibility of the customer to inform AAA Biotech
of any product performance
issues observed or experienced within 30 days of receipt of said product. To see additional
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