Typical Testing Data/Standard Curve (for reference only)
Mouse Matrix metalloproteinase-14 ELISA Kit | Mmp14 elisa kit
Mouse Matrix metalloproteinase-14 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme. Mice lacking the encoded protein exhibit craniofacial dysmorphism, arthritis, osteopenia, dwarfism, and fibrosis of soft tissues. [provided by RefSeq, Feb 2016]
Uniprot Description
MMP14: Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Up-regulated by NANOS1. Expressed in stromal cells of colon, breast, and head and neck. Expressed in lung tumors. Belongs to the peptidase M10A family.
Protein type: Protease; EC 3.4.24.80; Membrane protein, integral; Motility/polarity/chemotaxis
Cellular Component: cytoplasm; cytoplasmic vesicle; extracellular matrix; focal adhesion; integral to membrane; membrane; plasma membrane
Molecular Function: calcium ion binding; hydrolase activity; integrin binding; metal ion binding; metalloendopeptidase activity; metallopeptidase activity; peptidase activity; protease activator activity; zinc ion binding
Biological Process: branching morphogenesis of a tube; cell migration; collagen catabolic process; embryonic cranial skeleton morphogenesis; endochondral ossification; lung development; negative regulation of focal adhesion formation; negative regulation of Notch signaling pathway; ossification; positive regulation of B cell differentiation; positive regulation of cell growth; positive regulation of cell migration; proteolysis; response to hormone stimulus; tissue remodeling; zymogen activation
Research Articles on Mmp14
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Product Notes
The Mouse Mmp14 mmp14 (Catalog #AAA2882588) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2882588 ELISA Kit recognizes Mouse Mmp14. It is sometimes possible for the material contained within the vial of "Matrix metalloproteinase-14, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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