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Monocyte to macrophage differentiation protein (MMD) Recombinant Protein | MMD recombinant protein

Recombinant Human Monocyte to macrophage differentiation protein (MMD)

Gene Names
MMD; MMA; MMD1; PAQR11
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Monocyte to macrophage differentiation protein (MMD); Recombinant Human Monocyte to macrophage differentiation protein (MMD); MMD recombinant protein
Ordering
For Research Use Only!
Host
Cell Free Expression
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Liquid containing glycerol
Sequence Positions
1-238aa; full length protein
Sequence
MRFKNRFQRFMNHRAPANGRYKPTCYEHAANCYTHAFLIVPAIVGSALLHRLSDDCWEKI TAWIYGMGLCALFIVSTVFHIVSWKKSHLRTVEHCFHMCDRMVIYFFIAASYAPWLNLRE LGPLASHMRWFIWLMAAGGTIYVFLYHEKYKVVELFFYLTMGFSPALVVTSMNNTDGLQE LACGGLIYCLGVVFFKSDGIIPFAHAIWHLFVATAAAVHYYAIWKYLYRSPTDFMRHL
Sequence Length
Full length protein
Application Notes
This is a recombinant transmembrane protein expressed in a cell-free expression system.
Species
Human
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Product Categories/Family for MMD recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27,667 Da
NCBI Official Full Name
monocyte to macrophage differentiation factor
NCBI Official Synonym Full Names
monocyte to macrophage differentiation associated
NCBI Official Symbol
MMD
NCBI Official Synonym Symbols
MMA; MMD1; PAQR11
NCBI Protein Information
monocyte to macrophage differentiation factor
UniProt Protein Name
Monocyte to macrophage differentiation factor
UniProt Gene Name
MMD
UniProt Synonym Gene Names
PAQR11
UniProt Entry Name
PAQRB_HUMAN

NCBI Description

This protein is expressed by in vitro differentiated macrophages but not freshly isolated monocytes. Although sequence analysis identifies seven potential transmembrane domains, this protein has little homology to G-protein receptors and it has not been positively identified as a receptor. A suggested alternative function is that of an ion channel protein in maturing macrophages. [provided by RefSeq, Jul 2008]

Uniprot Description

MMD: Involved in the dynamics of lysosomal membranes associated with microglial activation following brain lesion. Belongs to the ADIPOR family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, misc.

Chromosomal Location of Human Ortholog: 17q

Cellular Component: Golgi apparatus; integral to plasma membrane; late endosome membrane; lysosomal membrane; membrane

Molecular Function: protein kinase activity; receptor activity

Biological Process: cytolysis; positive regulation of neuron differentiation; positive regulation of protein kinase activity; protein amino acid phosphorylation; regulation of protein localization

Research Articles on MMD

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Product Notes

The MMD mmd (Catalog #AAA7020391) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-238aa; full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the MMD mmd for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MRFKNRFQRF MNHRAPANGR YKPTCYEHAA NCYTHAFLIV PAIVGSALLH RLSDDCWEKI TAWIYGMGLC ALFIVSTVFH IVSWKKSHLR TVEHCFHMCD RMVIYFFIAA SYAPWLNLRE LGPLASHMRW FIWLMAAGGT IYVFLYHEKY KVVELFFYLT MGFSPALVVT SMNNTDGLQE LACGGLIYCL GVVFFKSDGI IPFAHAIWHL FVATAAAVHY YAIWKYLYRS PTDFMRHL. It is sometimes possible for the material contained within the vial of "Monocyte to macrophage differentiation protein (MMD), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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