Mouse MAP kinase interacting serine/threonine kinase 1 ELISA Kit | MKNK1 elisa kit
Mouse MAP kinase-interacting serine/threonine-protein kinase 1, MKNK1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a serine-threonine protein kinase that is activated by extracellular signal-regulated kinase or p38 mitogen-activated protein kinases, and it may function in cytokine and environmental stress responses. This kinase is required for phosphorylation of eukaryotic translation initiation factor 4E but it is not required for cell growth during development. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Oct 2013]
Uniprot Description
Mnk1: a CAM kinase of the MAPKKAPK family that can regulate translation. Following activation by MAP kinases, Mnk1 phosphorylates eIF4E at Ser209, increasing its affinity for the 7-methylguanosine-containing mRNA cap. Two MAPK phosphorylation sites in mouse Mnk1 (Thr197 and Thr202) are essential for its kinase activity. Three alternatively spliced human isoforms have been described.
Protein type: Kinase, protein; Protein kinase, CAMK; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Translation; CAMK group; MAPKAPK family; MNK subfamily
Cellular Component: cytoplasm; intracellular; nucleus
Molecular Function: calmodulin binding; transferase activity; protein serine/threonine kinase activity; calcium-dependent protein serine/threonine kinase activity; calmodulin-dependent protein kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; ATP binding; protein kinase activity
Biological Process: regulation of translation; peptidyl-serine phosphorylation; protein amino acid autophosphorylation; phosphorylation; protein amino acid phosphorylation; response to salt stress; regulation of translational initiation
Research Articles on MKNK1
Similar Products
Product Notes
The Mouse MKNK1 mknk1 (Catalog #AAA9338774) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9338774 ELISA Kit recognizes Mouse MKNK1. It is sometimes possible for the material contained within the vial of "MAP kinase interacting serine/threonine kinase 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
