Putative microRNA 17 host gene protein (MIR17HG) Recombinant Protein | MIR17HG recombinant protein
Recombinant Human Putative microRNA 17 host gene protein (MIR17HG), partial
Gene Names
MIR17HG; MIHG1; MIRH1; FGLDS2; MIRHG1; C13orf25; LINC00048; miR-17-92; NCRNA00048
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Putative microRNA 17 host gene protein (MIR17HG); Recombinant Human Putative microRNA 17 host gene protein (MIR17HG); partial; MIR17HG recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Length
32
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for MIR17HG recombinant protein
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
3,703 Da
NCBI Official Full Name
Putative microRNA 17 host gene protein
NCBI Official Synonym Full Names
miR-17-92a-1 cluster host gene
NCBI Official Symbol
MIR17HG
NCBI Official Synonym Symbols
MIHG1; MIRH1; FGLDS2; MIRHG1; C13orf25; LINC00048; miR-17-92; NCRNA00048
UniProt Protein Name
Putative microRNA 17 host gene protein
Protein Family
UniProt Gene Name
MIR17HG
UniProt Synonym Gene Names
C13orf25; MIRH1; MIRHG1
NCBI Description
This gene is the host gene for the MIR17-92 cluster, a group of at least six microRNAs (miRNAs) that may be involved in cell survival, proliferation, differentiation, and angiogenesis. Amplification of this gene has been found in several lymphomas and solid tumors. Two non-protein coding transcript variants have been found for this host gene, but only the longest is a polycistronic transcript containing the MIR17-92 cluster. [provided by RefSeq, May 2012]
Uniprot Description
MiscellaneousThe microRNAs that are encoded in a MIR17HG intron stimulate growth of cultured lung cancer cells.
Research Articles on MIR17HG
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Product Notes
The MIR17HG mir17hg (Catalog #AAA7087506) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Putative microRNA 17 host gene protein (MIR17HG), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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