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Typical Testing Data/Standard Curve (for reference only)

Mouse Methylated-DNA--protein-cysteine methyltransferase ELISA Kit | Mgmt elisa kit

Mouse Methylated-DNA--protein-cysteine methyltransferase ELISA Kit

Gene Names
Mgmt; AGT; Agat; AI267024
Reactivity
Mouse
Synonyms
Methylated-DNA--protein-cysteine methyltransferase; Mouse Methylated-DNA--protein-cysteine methyltransferase ELISA Kit; 6-O-methylguanine-DNA methyltransferase; MGMT; O-6-methylguanine-DNA-alkyltransferase; Mgmt; 2.1.1.63; Mgmt elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Sequence Length
211
Assay Type
Sandwich
Detection Range
78-5000 pg/mL
Sensitivity
39.9 pg/mL
Intra-Assay CV
<=6.9%
Inter-Assay CV
<=8.8%
Recovery
89%
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,435 Da
NCBI Official Full Name
methylated-DNA--protein-cysteine methyltransferase
NCBI Official Synonym Full Names
O-6-methylguanine-DNA methyltransferase
NCBI Official Symbol
Mgmt
NCBI Official Synonym Symbols
AGT; Agat; AI267024
NCBI Protein Information
methylated-DNA--protein-cysteine methyltransferase
UniProt Protein Name
Methylated-DNA--protein-cysteine methyltransferase
UniProt Gene Name
Mgmt
UniProt Synonym Gene Names
MGMT
UniProt Entry Name
MGMT_MOUSE

Uniprot Description

MGMT: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. Belongs to the MGMT family.

Protein type: Methyltransferase; DNA repair, damage; Apoptosis; Nuclear receptor co-regulator; EC 2.1.1.63

Cellular Component: membrane; nucleoplasm; nucleus

Molecular Function: calcium ion binding; catalytic activity; damaged DNA binding; DNA binding; metal ion binding; methylated-DNA-[protein]-cysteine S-methyltransferase activity; methyltransferase activity; transferase activity

Biological Process: DNA dealkylation; DNA repair; methylation; positive regulation of DNA repair; regulation of caspase activity; response to DNA damage stimulus

Research Articles on Mgmt

Similar Products

Product Notes

The Mouse Mgmt mgmt (Catalog #AAA2880595) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2880595 ELISA Kit recognizes Mouse Mgmt. It is sometimes possible for the material contained within the vial of "Methylated-DNA--protein-cysteine methyltransferase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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