Multidrug resistance-like ATP-binding protein MdlA (mdlA) Recombinant Protein | mdlA recombinant protein
Recombinant Escherichia coli Multidrug resistance-like ATP-binding protein MdlA (mdlA)
NCBI and Uniprot Product Information
NCBI Description
Although MdlAB are similar to multidrug exporters, no overexpression resistances were found. mdlA and mdlB were fused by a frameshift mutation or sequencing error in the original report. mdlA and mdlB were fused by a frameshift mutation or sequencing error in the original report. [More information is available at EcoGene: EG11622]. MdlA and MdlB are uncharacterized members of the ABC superfamily of transporters . [More information is available at EcoCyc: G6248].
Uniprot Description
Catalytic activity: ATP + H2O + xenobiotic(In) = ADP + phosphate + xenobiotic(Out).
Subcellular location: Cell inner membrane; Multi-pass membrane protein Ref.5.
Sequence similarities: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. [View classification]Contains 1 ABC transmembrane type-1 domain.Contains 1 ABC transporter domain.
Sequence caution: The sequence AAC36870.1 differs from that shown. Reason: Frameshift at position 546. Fuses together mdlA and mdlB.
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Product Notes
The mdlA mdla (Catalog #AAA1237344) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-590. The amino acid sequence is listed below: MRLFAQLSWY FRREWRRYLG AVALLVIIAM LQLVPPKVVG IVVDGVTEQH FTTGQILMWI ATMVLIAVVV YLLRYVWRVL LFGASYQLAV ELREDYYRQL SRQHPEFYLR HRTGDLMARA TNDVDRVVFA AGEGVLTLVD SLVMGCAVLI MMSTQISWQL TLFSLLPMPV MAIMIKRNGD ALHERFKLAQ AAFSSLNDRT QESLTSIRMI KAFGLEDRQS ALFAADAEDT GKKNMRVARI DARFDPTIYI AIGMANLLAI GGGSWMVVQG SLTLGQLTSF MMYLGLMIWP MLALAWMFNI VERGSAAYSR IRAMLAEAPV VNDGSEPVPE GRGELDVNIH QFTYPQTDHP ALENVNFALK PGQMLGICGP TGSGKSTLLS LIQRHFDVSE GDIRFHDIPL TKLQLDSWRS RLAVVSQTPF LFSDTVANNI ALGCPNATQQ EIEHVARLAS VHDDILRLPQ GYDTEVGERG VMLSGGQKQR ISIARALLVN AEILILDDAL SAVDGRTEHQ ILHNLRQWGQ GRTVIISAHR LSALTEASEI IVMQHGHIAQ RGNHDVLAQQ SGWYRDMYRY QQLEAALDDA PENREEAVDA. It is sometimes possible for the material contained within the vial of "Multidrug resistance-like ATP-binding protein MdlA (mdlA), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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