Cell surface glycoprotein MUC18 (MCAM) Recombinant Protein | MCAM recombinant protein
Recombinant Human Cell surface glycoprotein MUC18 (MCAM), partial
Gene Names
MCAM; CD146; MUC18
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Cell surface glycoprotein MUC18 (MCAM); Recombinant Human Cell surface glycoprotein MUC18 (MCAM); partial; MCAM recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
50-646, Partial.
Sequence
LSQSQGNLSHVDWFSVHKEKRTLIFRVRQGQGQSEPGEYEQRLSLQDRGATLALTQVTPQDERIFLCQGKRPRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCVGRNGYPIPQVIWYKNGRPLKEEKNRVHIQSSQTVESSGLYTLQSILKAQLVKEDKDAQFYCELNYRLPSGNHMKESREVTVPVFYPTEKVWLEVEPVGMLKEGDRVEIRCLADGNPPPHFSISKQNPSTREAEEETTNDNGVLVLEPARKEHSGRYECQGLDLDTMISLLSEPQELLVNYVSDVRVSPAAPERQEGSSLTLTCEAESSQDLEFQWLREETGQVLERGPVLQLHDLKREAGGGYRCVASVPSIPGLNRTQLVNVAIFGPPWMAFKERKVWVKENMVLNLSCEASGHPRPTISWNVNGTASEQDQDPQRVLSTLNVLVTPELLETGVECTASNDLGKNTSILFLELVNLTTLTPDSNTTTGLSTSTASPHTRANSTSTERKLPEPESRGVVIVAVIVCILVLAVLGAVLYFLYKKGKLPCRRSGKQEITLPPSRKSELVVEVKSDKLPEEMGLLQGSSGDKRAPGDQGEKYIDLRH
Sequence Length
646
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
57,605 Da
NCBI Official Full Name
cell surface glycoprotein MUC18
NCBI Official Synonym Full Names
melanoma cell adhesion molecule
NCBI Official Symbol
MCAM
NCBI Official Synonym Symbols
CD146; MUC18
NCBI Protein Information
cell surface glycoprotein MUC18
UniProt Protein Name
Cell surface glycoprotein MUC18
Protein Family
UniProt Gene Name
MCAM
UniProt Synonym Gene Names
MUC18
Uniprot Description
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
Research Articles on MCAM
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Product Notes
The MCAM mcam (Catalog #AAA718786) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 50-646, Partial. The amino acid sequence is listed below: LSQSQGNLSH VDWFSVHKEK RTLIFRVRQG QGQSEPGEYE QRLSLQDRGA TLALTQVTPQ DERIFLCQGK RPRSQEYRIQ LRVYKAPEEP NIQVNPLGIP VNSKEPEEVA TCVGRNGYPI PQVIWYKNGR PLKEEKNRVH IQSSQTVESS GLYTLQSILK AQLVKEDKDA QFYCELNYRL PSGNHMKESR EVTVPVFYPT EKVWLEVEPV GMLKEGDRVE IRCLADGNPP PHFSISKQNP STREAEEETT NDNGVLVLEP ARKEHSGRYE CQGLDLDTMI SLLSEPQELL VNYVSDVRVS PAAPERQEGS SLTLTCEAES SQDLEFQWLR EETGQVLERG PVLQLHDLKR EAGGGYRCVA SVPSIPGLNR TQLVNVAIFG PPWMAFKERK VWVKENMVLN LSCEASGHPR PTISWNVNGT ASEQDQDPQR VLSTLNVLVT PELLETGVEC TASNDLGKNT SILFLELVNL TTLTPDSNTT TGLSTSTASP HTRANSTSTE RKLPEPESRG VVIVAVIVCI LVLAVLGAVL YFLYKKGKLP CRRSGKQEIT LPPSRKSELV VEVKSDKLPE EMGLLQGSSG DKRAPGDQGE KYIDLRH . It is sometimes possible for the material contained within the vial of "Cell surface glycoprotein MUC18 (MCAM), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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