Mouse membrane-bound transcription factor peptidase, site 1 ELISA Kit | MBTPS1 elisa kit

Mouse Membrane-bound transcription factor site-1 protease, MBTPS1 ELISA Kit

Cat. Num. AAA9328450

• Gene Names: Mbtps1; S1P; Ski1; SKI-1; AV003995; mKIAA0091; 0610038M03Rik
• Reactivity: Mouse
• Synonyms: membrane-bound transcription factor peptidase; site 1; Mouse Membrane-bound transcription factor site-1 protease; MBTPS1 ELISA Kit; Mouse Membrane-bound transcription factor site-1 protease (MBTPS1) ELISA kit; KIAA0091; MGC138711; MGC138712; PCSK8; S1P; SKI-1; membrane-bound transcription factor protease; membrane-bound transcription factor site-1 protease; site-1 protease; subtilisin/kexin isozyme-1; MBTPS1 elisa kit

• Reactivity: Mouse
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Assay Type: Quantitative Sandwich
• Detection Range: 0.25 ng/ml - 8 ng/ml
• Sensitivity: 0.1 ng/ml
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for MBTPS1 elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of MBTPS1 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 268836232
• NCBI GeneID: 56453
• NCBI Accession #: NP_001161382.1
• NCBI GenBank Nucleotide #: NM_001167910.1
• UniProt Accession #: Q9WTZ2; Q6PG67
• Molecular Weight: 117,457 Da
• NCBI Official Full Name: membrane-bound transcription factor site-1 protease
• NCBI Official Synonym Full Names: membrane-bound transcription factor peptidase, site 1
• NCBI Official Symbol: Mbtps1
• NCBI Official Synonym Symbols: S1P; Ski1; SKI-1; AV003995; mKIAA0091; 0610038M03Rik
• NCBI Protein Information: membrane-bound transcription factor site-1 protease; S1P endopeptidase; endopeptidase S1P; subtilisin/kexin isozyme 1; subtilisin/kexin isozyme-1; subtilisin/kexin isozyme SKI-1; sterol-regulated luminal protease; membrane-bound transcription factor protease, site 1
• UniProt Protein Name: Membrane-bound transcription factor site-1 protease
• Protein Family: Membrane-bound transcription factor site-1 protease
• UniProt Gene Name: Mbtps1
• UniProt Synonym Gene Names: S1p; Ski1; SKI-1
• UniProt Entry Name: MBTP1_MOUSE

Uniprot Description

MBTPS1: Catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His- Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Belongs to the peptidase S8 family.

Protein type: Protease; EC 3.4.21.112; Membrane protein, integral; Endoplasmic reticulum

Cellular Component: Golgi apparatus; Golgi stack; membrane; endoplasmic reticulum; integral to membrane

Molecular Function: peptidase activity; hydrolase activity; serine-type peptidase activity; serine-type endopeptidase activity; endopeptidase activity

Biological Process: steroid metabolic process; cholesterol metabolic process; regulation of transcription factor import into nucleus; lysosome organization and biogenesis; lipid metabolic process; proteolysis