MAP3K12-Binding Inhibitory Protein 1/MBIPP Recombinant Protein | MBIPP recombinant protein

Recombinant Human MAP3K12-Binding Inhibitory Protein 1/MBIPP Protein (N-6His)

Cat. Num. AAA2552947

• Purity: >95% as determined by reducing SDS-PAGE.
• Synonyms: MAP3K12-Binding Inhibitory Protein 1/MBIPP; Recombinant Human MAP3K12-Binding Inhibitory Protein 1/MBIPP Protein (N-6His); MAP3K12-Binding Inhibitory Protein 1; MAPK Upstream Kinase-Binding Inhibitory Protein; MUK-Binding Inhibitory Protein; MBIP; MBIPP recombinant protein

• Host: E Coli
• Purity/Purification: >95% as determined by reducing SDS-PAGE.
• Form/Format: Lyophilized from a 0.2 mum filtered solution of 20mM Tris, pH 8.0.
• Sequence Positions: Met1-Pro344
• Sequence Length: 343

• Species: Human
• Endotoxin: <1.0 EU per ug as determined by LAL test.
• Fusion Tag: N-6His
• Preparation and Storage: Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.; Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.

Related Product Information for MBIPP recombinant protein

MAP3K12-binding inhibitory protein 1 (MBIP) is a 39kD protein high expression in the heart and lung. It is a component of the ADA2A-containing complex (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4, and composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts directly with KAT2A, CSRP2BP and WDR5. It's function to inhibit the MAP3K12 activity to induce the activation of the JNK/SAPK pathway.

NCBI and Uniprot Product Information

• NCBI GI #: 222080055
• NCBI GeneID: 51562
• NCBI Accession #: NP_001138363.1
• NCBI GenBank Nucleotide #: NM_001144891.1
• UniProt Accession #: Q9NS73; Q86TZ2; Q96AS5; Q9BS93; Q9NZE1
• Molecular Weight: Molecular Mass: 42.5 kDa; Actual Protein Molecular Mass: 50 kDa
• NCBI Official Full Name: MAP3K12-binding inhibitory protein 1 isoform 2
• NCBI Official Synonym Full Names: MAP3K12 binding inhibitory protein 1
• NCBI Official Symbol: MBIP
• NCBI Protein Information: MAP3K12-binding inhibitory protein 1
• UniProt Protein Name: MAP3K12-binding inhibitory protein 1
• UniProt Gene Name: MBIP
• UniProt Synonym Gene Names: MUK-binding inhibitory protein

Uniprot Description

Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.