Rat megakaryocyte-associated tyrosine kinase ELISA Kit | MATK elisa kit

Rat Megakaryocyte-associated tyrosine-protein kinase, MATK ELISA Kit

Cat. Num. AAA9340180

• Gene Names: Matk; Batk
• Reactivity: Rat
• Synonyms: megakaryocyte-associated tyrosine kinase; Rat Megakaryocyte-associated tyrosine-protein kinase; MATK ELISA Kit; Rat Megakaryocyte-associated tyrosine-protein kinase (MATK) ELISA kit; CHK; CTK; DKFZp434N1212; HHYLTK; HYL; HYLTK; Lsk; MGC1708; MGC2101; Csk-homologous kinase; Csk-type protein tyrosine kinase; HYL tyrosine kinase; hematopoietic consensus tyrosine-lacking kinase; hydroxy; MATK elisa kit

• Reactivity: Rat

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 11177904
• NCBI GeneID: 60450
• NCBI Accession #: NP_068631.1
• NCBI GenBank Nucleotide #: NM_021859.2
• UniProt Accession #: P41243
• Molecular Weight: 51,897 Da
• NCBI Official Full Name: megakaryocyte-associated tyrosine-protein kinase
• NCBI Official Synonym Full Names: megakaryocyte-associated tyrosine kinase
• NCBI Official Symbol: Matk
• NCBI Official Synonym Symbols: Batk
• NCBI Protein Information: megakaryocyte-associated tyrosine-protein kinase; protein kinase BATK; tyrosine-protein kinase CTK; non-receptor protein kinase protein; megakaryocyte-associated tyrosine kinase (non-receptor protein tyrosine kinase)
• UniProt Protein Name: Megakaryocyte-associated tyrosine-protein kinase
• Protein Family: Maturase
• UniProt Gene Name: Matk
• UniProt Synonym Gene Names: Batk; Ctk
• UniProt Entry Name: MATK_RAT

NCBI Description

a non-receptor protein tyrosine kinase [RGD, Feb 2006]

Uniprot Description

CTK: a non-receptor tyrosine kinase. Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation. Expressed in cancerous but not normal breast tissue; interacts with activated ERBB2 receptor and is likely to inhibit proliferation.

Protein type: Kinase, protein; EC 2.7.10.2; Protein kinase, tyrosine (non-receptor); Protein kinase, TK; TK group; Csk family

Cellular Component: extrinsic to internal side of plasma membrane; cytoplasm

Molecular Function: non-membrane spanning protein tyrosine kinase activity; ATP binding; receptor binding

Biological Process: cell migration; morphogenesis of an epithelium; innate immune response; cell differentiation; transmembrane receptor protein tyrosine kinase signaling pathway; regulation of cell proliferation