Bovine mitogen-activated protein kinase 7 ELISA Kit | MAPK7 elisa kit
Bovine Mitogen-activated protein kinase 7, MAPK7 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Function: Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction
Catalytic activity: ATP + a protein = ADP + a phosphoprotein.
Cofactor: Magnesium
Enzyme regulation: Activated by tyrosine and threonine phosphorylation. Activated in response to hyperosmolarity, hydrogen peroxide, and epidermal growth factor (EGF)
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Product Notes
The Bovine MAPK7 mapk7 (Catalog #AAA9323998) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9323998 ELISA Kit recognizes Bovine MAPK7. It is sometimes possible for the material contained within the vial of "mitogen-activated protein kinase 7, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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