Mouse mitogen-activated protein kinase kinase 5 ELISA Kit | MAP2K5 elisa kit
Mouse Dual specificity mitogen-activated protein kinase kinase 5, MAP2K5 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
MEK5: a dual specificity protein kinase of the STE7 family. Activates ERK5 and is itself phosphorylated and activated by MEKK3, as well as by atypical protein kinase C isoforms. Involved in growth factor stimulated cell proliferation and muscle cell differentiation. Four alternatively spliced isoforms have been described.
Protein type: Protein kinase, dual-specificity (non-receptor); Protein kinase, STE; Kinase, protein; EC 2.7.12.2; STE group; STE7 family
Cellular Component: cytoplasm; spindle; intracellular; nucleus; cytosol
Molecular Function: transferase activity; MAP kinase kinase activity; protein serine/threonine kinase activity; protein binding; protein-tyrosine kinase activity; metal ion binding; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; ATP binding; protein kinase activity
Biological Process: negative regulation of heterotypic cell-cell adhesion; activation of MAPK activity; heart development; MAPKKK cascade; negative regulation of interleukin-8 biosynthetic process; negative regulation of caspase activity; negative regulation of transcription from RNA polymerase II promoter; protein amino acid phosphorylation; positive regulation of cell growth; positive regulation of protein metabolic process; inhibition of NF-kappaB transcription factor; positive regulation of transcription from RNA polymerase II promoter; phosphorylation; positive regulation of epithelial cell proliferation
Research Articles on MAP2K5
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Product Notes
The Mouse MAP2K5 map2k5 (Catalog #AAA9319233) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9319233 ELISA Kit recognizes Mouse MAP2K5. It is sometimes possible for the material contained within the vial of "mitogen-activated protein kinase kinase 5, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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