Microtubule-associated protein 2 Recombinant Protein | Map2 recombinant protein

Recombinant Mouse Microtubule-associated protein 2

Cat. Num. AAA966140

• Gene Names: Map2; MAP-2; Mtap2; Mtap-2; repro4; G1-397-34
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Microtubule-associated protein 2; Recombinant Mouse Microtubule-associated protein 2; Map2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 213-559aa; Partial
• Sequence: GMEGEKLPPVPFAQTFGTNLEDRKQSTEPSIVMPSIGLSAEPPAPKEPKDWFIEMPTESKKDEWGLAAPISPGPLTPMREKDVLEDIPRWEGKQFDSPMPSPFHGGSFTLPLDTMKNERVSEGPRPFAPVFFQSDDKVSLQDPSALATSKESSKDEEPLKDKADKVADVSISEVTTLLGNVHSPVVEGYVGENISGEVKVTTDQEKKETSAPSVQEPTLTETEPQTKLDEKSTVSIEEAVAKKEESFKLRDDKTGVIQTSTEQSFSKEDQKGQEHTIDELKQDSFPISLEQAVTDAAMTSKTLGKVTSEPEAVSERREIQGLFEEKTADKNKLEGAGSATIAEVEMP
• Sequence Length: 1828

• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

Related Product Information for Map2 recombinant protein

The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also se to have a stiffening effect on microtubules.

References

Complete sequence of a cDNA encoding mouse MAP2.Wang D., Lewis S.A., Cowan N.J.Nucleic Acids Res. 16:11369-11370(1988) Microtubule-associated protein MAP2 shares a microtubule binding motif with tau protein.Lewis S.A., Wang D., Cowan N.J.Science 242:936-939(1988) Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.PLoS Biol. 7:E1000112-E1000112(2009) Lubec G., Sunyer B., Chen W.-Q.Submitted (JAN-2009) to UniProtKB Phosphoproteomic analysis of the developing mouse brain.Ballif B.A., Villen J., Beausoleil S.A., Schwartz D., Gygi S.P.Mol. Cell. Proteomics 3:1093-1101(2004) Comprehensive identification of phosphorylation sites in postsynaptic density preparations.Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L.Mol. Cell. Proteomics 5:914-922(2006) Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.Munton R.P., Tweedie-Cullen R., Livingstone-Zatchej M., Weinandy F., Waidelich M., Longo D., Gehrig P., Potthast F., Rutishauser D., Gerrits B., Panse C., Schlapbach R., Mansuy I.M.Mol. Cell. Proteomics 6:283-293(2007)

NCBI and Uniprot Product Information

• NCBI GI #: 890810631
• NCBI GeneID: 17756
• NCBI Accession #: NP_001297563.1
• NCBI GenBank Nucleotide #: NM_001310634.1
• UniProt Accession #: P20357; E9QLE1
• Molecular Weight: 40 kDa
• NCBI Official Full Name: microtubule-associated protein 2 isoform 3
• NCBI Official Synonym Full Names: microtubule-associated protein 2
• NCBI Official Symbol: Map2
• NCBI Official Synonym Symbols: MAP-2; Mtap2; Mtap-2; repro4; G1-397-34
• NCBI Protein Information: microtubule-associated protein 2
• UniProt Protein Name: Microtubule-associated protein 2
• Protein Family: Microtubule-associated protein
• UniProt Gene Name: Map2
• UniProt Synonym Gene Names: Mtap2; MAP-2
• UniProt Entry Name: MTAP2_MOUSE

Uniprot Description

MAP2: a member of the microtubule-associated protein (MAP) family. Its exact function is unknown but MAPs appear to stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. Expressed at high levels in neural tissue and the prostate. Four alternatively spliced transcript variants have been reported.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Cellular Component: cell soma; cytoplasm; cytoskeleton; dendrite; dendritic shaft; intracellular; microtubule; microtubule associated complex; neuron projection; nucleolus; postsynaptic density; protein complex; rough endoplasmic reticulum; smooth endoplasmic reticulum

Molecular Function: calmodulin binding; cytoskeletal regulatory protein binding; microtubule binding; protein binding; tubulin binding

Biological Process: axonogenesis; central nervous system neuron development; dendrite development; establishment of cell polarity; microtubule bundle formation; regulation of axonogenesis