Human Amine oxidase [flavin-containing] B ELISA Kit | MAOB elisa kit

Human Amine oxidase [flavin-containing] B ELISA Kit

Cat. Num. AAA2887298

• Reactivity: Human
• Synonyms: Amine oxidase [flavin-containing] B; Human Amine oxidase [flavin-containing] B ELISA Kit; Monoamine oxidase type B; MAO-B; MAOB; 1.4.3.4; MAOB elisa kit

• Reactivity: Human
• Sequence Length: 520

• Assay Type: Sandwich
• Detection Range: 0.156-10 ng/mL
• Sensitivity: 0.056ng/mL
• Intra-Assay CV: <=4.3%
• Inter-Assay CV: <=6.8%
• Recovery: 89%
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 38202207
• NCBI GeneID: 4129
• NCBI Accession #: NP_000889.3
• NCBI GenBank Nucleotide #: NM_000898.4
• UniProt Accession #: P27338; Q7Z6S2; B2R6R3; B7Z5H3; D3DWC3
• Molecular Weight: 46,539 Da
• NCBI Official Full Name: amine oxidase
• NCBI Official Synonym Full Names: monoamine oxidase B
• NCBI Official Symbol: MAOB
• NCBI Protein Information: amine oxidase [flavin-containing] B
• UniProt Protein Name: Amine oxidase [flavin-containing] B
• Protein Family: Amine oxidase
• UniProt Gene Name: MAOB
• UniProt Synonym Gene Names: MAO-B
• UniProt Entry Name: AOFB_HUMAN

NCBI Description

The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008]

Uniprot Description

MAOB: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. Belongs to the flavin monoamine oxidase family.

Protein type: Amino Acid Metabolism - glycine, serine and threonine; Membrane protein, integral; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - tryptophan; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Amino Acid Metabolism - tyrosine; Mitochondrial; EC 1.4.3.4; Oxidoreductase; Amino Acid Metabolism - histidine; Amino Acid Metabolism - arginine and proline

Chromosomal Location of Human Ortholog: Xp11.23

Cellular Component: integral to membrane; mitochondrial envelope; mitochondrial inner membrane; mitochondrial outer membrane; mitochondrion

Molecular Function: amine oxidase activity; electron carrier activity; FAD binding; protein homodimerization activity

Biological Process: dopamine catabolic process; hydrogen peroxide biosynthetic process; negative regulation of serotonin secretion; positive regulation of dopamine metabolic process; response to aluminum ion; response to corticosterone stimulus; response to drug; response to ethanol; response to lipopolysaccharide; response to selenium ion; response to toxin; substantia nigra development; xenobiotic metabolic process