Human Glycoprotein endo-alpha-1, 2-mannosidase ELISA Kit | MANEA elisa kit
Human Glycoprotein endo-alpha-1, 2-mannosidase ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005 [PubMed 15677381]).[supplied by OMIM, Sep 2008]
Uniprot Description
MANEA: Belongs to the glycosyl hydrolase 99 family
Protein type: EC 3.2.1.130; Hydrolase; Membrane protein, integral
Chromosomal Location of Human Ortholog: 6q16.1
Cellular Component: Golgi apparatus; Golgi membrane
Molecular Function: glycoprotein endo-alpha-1,2-mannosidase activity
Research Articles on MANEA
Similar Products
Product Notes
The Human MANEA manea (Catalog #AAA9425294) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9425294 ELISA Kit recognizes Human MANEA. It is sometimes possible for the material contained within the vial of "Glycoprotein endo-alpha-1, 2-mannosidase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
