Human melanoma antigen family B, 2 ELISA Kit | MAGEB2 elisa kit
Human Melanoma-associated antigen B2, MAGEB2 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008]
Uniprot Description
MAGE-B2: May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.
Protein type: Cancer Testis Antigen (CTA)
Chromosomal Location of Human Ortholog: Xp21.3
Research Articles on MAGEB2
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Product Notes
The Human MAGEB2 mageb2 (Catalog #AAA9322277) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9322277 ELISA Kit recognizes Human MAGEB2. It is sometimes possible for the material contained within the vial of "melanoma antigen family B, 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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