Macrolide export ATP-binding/permease protein MacB 3 (macB3) Recombinant Protein | Pden_5133 recombinant protein
Recombinant Paracoccus denitrificans Macrolide export ATP-binding/permease protein MacB 3 (macB3)
NCBI and Uniprot Product Information
Uniprot Description
Function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation
By similarity.
Subunit structure: Homodimer
By similarity.
Subcellular location: Cell inner membrane; Multi-pass membrane protein
Potential.
Domain: In MacB the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused.
Miscellaneous: The complex MacAB-TolC (OMF) forms a single transport channel across the two membranes, allowing direct export of macrolide. This channel is involved in type 1 secretion system
By similarity.
Sequence similarities: Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family. [View classification]Contains 1 ABC transporter domain.
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Product Notes
The Pden_5133 macb3 (Catalog #AAA1206371) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-640. The amino acid sequence is listed below: MPLIRIRGLH RVFGEGAARA HVLRGIDLDI HAGEFVAIVG TSGSGKSTLM NILGLLDRPS AGSYHLAGKD VARLSRDARA GLRNRLFGFV FQQYNLIPTL TALENVELPA SHAGAAREAR RARAAALLRS LGLGHRLTAR PLQMSGGQQQ RVSIARALMN GGAVILADEP TGALDAESGR QVMRLLSDLA GRGHTVILIT HDTDIAARAG RVIRVGEGRI AGDSGTRAAG PAVPVLPETT GSRSAFLHAL REAARSALAA IGASPVRTAL TLSGIVIGVA SVVAMLAIGR GAQEEFVKRA SAIGTNWVVV GSDQDTRMPR RPLTLDDAMA LKGLPNVAGV MPGRWEQATV RAGAFSIDTD IIGTDRDFRG VHGWDVVRGS FFSEADERGG SPVLLLGSTV AGTLFPDGRD PTGEFVFVNM SPFLVGGVLE SKGLSENGSD RDKVVAMPLR SLESRVYGPG ELSVIVVALQ DMARLDESNA LLREAMIRRH GTEDFWLADA AGAFAAAEAD RASQNLLLGA VATISIFVGG IGVMNIMFIT VRERTREIGI RSATGAAMRD ILVQFLTEAT VLSALGGLAG LALAVGIGAV AALGLGMPVV FSVTVALGAL AGATAMGAAF GLVPAIRAAR LSPVEALASP. It is sometimes possible for the material contained within the vial of "Macrolide export ATP-binding/permease protein MacB 3 (macB3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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