Outer capsid protein mu-1 (M2) Recombinant Protein | M2 recombinant protein
Recombinant Reovirus type 3 Outer capsid protein mu-1 (M2), partial
NCBI and Uniprot Product Information
Uniprot Description
Major outer capsid protein involved in host cell membrane penetration. In the endocytic compartment, outer-capsid protein sigma-3 is removed by cathepsin proteases, which exposes the viral membrane-penetration protein mu-1. Both myristoylated peptides mu-1N and phi are released during infectious subvirion particles (ISVP) formation in the endosome. They associate with host membranes and mu-1N induces permeabilization and delivery of transcriptionally active viral particles into the host cell cytoplasm. Seems to induce apoptosis in the host cell ().
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Product Notes
The M2 m2 (Catalog #AAA1184018) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-500. Partial. The amino acid sequence is listed below: GNASSIVQTI NVTGDGNVFK PSAETSSTAV PSLSLSPGML NPGGVPWIAV GDETSVTSPG ALRRMTSKDI PETAIINTDN SSGAVPSESA LVPYIDEPLV VVTEHAITNF TKAEMALEFN REFLDKMRVL SVSPKYSDLL TYVDCYVGVS ARQALNNFQK QVPVITPTRQ TMYVDSIQAA LKALEKWEID LRVAQTLLPT NVPIGEVSCP MQSVVKLLDD QLPDDSLIRR YPKEAAVALA KRNGGIQWMD VSEGTVMNEA VNAVAASALA PSASAPPLEE KSKLTEQAMD LVTAAEPEII ASLAPVPAPV FAIPPKPADY NVRTLRIDEA TWLRMIPKSM NTPFQIQVTD NTGTNWHLNL RGGTRVVNLD QIAPMRFVLD LGGKSYKETS WDPNGKKVGF IVFQSKIPFE LWTAASQIGQ ATVVNYVQLY AEDSSFTAQS IIATTSLAYN YEPEQLNKTD PEMNYYLLAT FIDSAAITPT NMTQPDVWDA LLTMSPLSA. It is sometimes possible for the material contained within the vial of "Outer capsid protein mu-1 (M2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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