Transmembrane O-methyltransferase (LRTOMT) Recombinant Protein | LRTOMT recombinant protein
Recombinant Propithecus coquereli Transmembrane O-methyltransferase (LRTOMT)
NCBI and Uniprot Product Information
Uniprot Description
Function: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Required for auditory function
By similarity. UniProtKB Q8WZ04 UniProtKB P21964
Catalytic activity: S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol. UniProtKB P21964
Subcellular location: Isoform 1: Membrane; Single-pass membrane protein
Potential. Isoform 2: Cytoplasm
By similarity UniProtKB A1Y9I9.
Miscellaneous: In primates, this protein is produced by a bicistronic gene which also produces the LRRC51 protein from an overlapping reading frame. In rodents, these proteins are produced by 2 separate adjacent genes which together are orthologous to the single primate gene. Ref.1
Sequence similarities: Belongs to the methyltransferase superfamily. Catechol-O-methyltransferase family.
Sequence caution: The sequence ACF40897.1 differs from that shown. Reason: Frameshift at position 12.
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Product Notes
The Transmembrane O-methyltransferase (LRTOMT) lrtomt (Catalog #AAA1257309) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-274. The amino acid sequence is listed below: MGTPWRKRKG ITQVGTMSPA IALAFLPLVV TLLVRYRHYF RLLVGTVLLR SLRDCLSGLR IEERAFSYVL THALPGDPGH ILTTLDHWSS HCEYLSHMGP VKGQILMRLV EEKAPACVLE LGTYCGYSTL LIAQALPPGG RLLTVERDPR TAAVAEKLIR LAGFDEHMVE LIVGSSEEVI PCLRTQYQLS RADLVLLIHR PRCYLRDLQL LEAHALLPAG ATVLADHVLF PGAPRFLQYA KSCGRYRCRL YHTGLPDFPA IKDGIAQLTY AGPG. It is sometimes possible for the material contained within the vial of "Transmembrane O-methyltransferase (LRTOMT), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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