Phospholysine Phosphohistidine Inorganic Pyrophosphate Phosphatase Recombinant Protein | LHPP recombinant protein
Recombinant Human Phospholysine Phosphohistidine Inorganic Pyrophosphate Phosphatase
Gene Names
LHPP; HDHD2B
Purity
Greater than 90.0% as determined by SDS-PAGE.
Synonyms
Phospholysine Phosphohistidine Inorganic Pyrophosphate Phosphatase; Recombinant Human Phospholysine Phosphohistidine Inorganic Pyrophosphate Phosphatase; LHPP Human; Phospholysine Phosphohistidine Inorganic Pyrophosphate Phosphatase Human Recombinant; Phospholysine phosphohistidine inorganic pyrophosphate phosphatase; hLHPP; LHPP; HDHD2B; LHPP recombinant protein
Host
E Coli
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Form/Format
The LHPP solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 10% glycerol and 0.1M NaCl.
Sterile Filtered colorless solution.
Sterile Filtered colorless solution.
Sequence
MRGSHHHHHP WYASMTGGQQ MGRDLYDDDD KDRWGSHMAP WGKRLAGVRG VLLDISGVLY DSGAGGGTAI AGSVEAVARL KRSRLKVRFC TNESQKSRAE LVGQLQRLGF DISEQEVTAP APAACQILKE QGLRPYLLIH DGVRSEFDQI DTSNPNCVVI ADAGESFSYQ NMNNAFQVLM ELEKPVLISL GKGRYYKETS GLMLDVGPYM KALEYACGIK AEVVGKPSPE FFKSALQAIG VEAHQAVMIG DDIVGDVGGA QRCGMRALQV RTGKFRPSDE HHPEVKADGY VDNLAEAVDL LLQHADK.
Sequence Length
210
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Related Product Information for LHPP recombinant protein
Description: LHPP Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 307 amino acids (1-270) and having a molecular mass of 33.5kDa.LHPP is fused to a 37 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (LHPP) belongs to the HAD-like hydrolase superfamily. LHPP is an exceptional enzyme which hydrolyzes not only oxygen-phosphorus bonds in inorganic pyrophosphate but also nitrogen-phosphorus bonds in phospholysine, phosphohistidine and imidodiphosphate in vitro. LHPP is expressed in the liver, kidney and moderately in the brain.
Introduction: Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (LHPP) belongs to the HAD-like hydrolase superfamily. LHPP is an exceptional enzyme which hydrolyzes not only oxygen-phosphorus bonds in inorganic pyrophosphate but also nitrogen-phosphorus bonds in phospholysine, phosphohistidine and imidodiphosphate in vitro. LHPP is expressed in the liver, kidney and moderately in the brain.
Product Categories/Family for LHPP recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
22,696 Da
NCBI Official Full Name
phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform 2
NCBI Official Synonym Full Names
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
NCBI Official Symbol
LHPP
NCBI Official Synonym Symbols
HDHD2B
NCBI Protein Information
phospholysine phosphohistidine inorganic pyrophosphate phosphatase; hLHPP
UniProt Protein Name
Phospholysine phosphohistidine inorganic pyrophosphate phosphatase
UniProt Gene Name
LHPP
UniProt Synonym Gene Names
hLHPP
UniProt Entry Name
LHPP_HUMAN
Uniprot Description
LHPP: Phosphatase that hydrolyzes imidodiphosphate, 3- phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency. Belongs to the HAD-like hydrolase superfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Energy Metabolism - oxidative phosphorylation; Mitochondrial; Hydrolase; EC 3.6.1.1
Chromosomal Location of Human Ortholog: 10q26.13
Cellular Component: nucleoplasm; cytoplasm; nucleus; cytosol
Molecular Function: inorganic diphosphatase activity; protein homodimerization activity; magnesium ion binding; phosphohistidine phosphatase activity
Biological Process: protein amino acid dephosphorylation; phosphate metabolic process
Research Articles on LHPP
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Product Notes
The LHPP lhpp (Catalog #AAA144763) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MRGSHHH HHP WYASMTGGQQ MGRDLYDDDD KDRWGSHMAP WGKRLAGVRG VLLDISGVLY DSGAGGGTAI AGSVEAVARL KRSRLKVRFC TNESQKSRAE LVGQLQRLGF DISEQEVTAP APAACQILKE QGLRPYLLIH DGVRSEFDQI DTSNPNCVVI ADAGESFSYQ NMNNAFQVLM ELEKPVLISL GKGRYYKETS GLMLDVGPYM KALEYACGIK AEVVGKPSPE FFKSALQAIG VEAHQAVMIG DDIVGDVGGA QRCGMRALQV RTGKFRPSDE HHPEVKADGY VDNLAEAVDL LLQHADK.. It is sometimes possible for the material contained within the vial of "Phospholysine Phosphohistidine Inorganic Pyrophosphate Phosphatase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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